Abstract: The present disclosure discloses a bioengineered formulation comprising: (a) a modified collagen peptide having a molecular weight in the range of 20-80 kDa, and with a degree of substitution in the range of 20-75%; and (b) a modified hyaluronic acid having a molecular weight in the range of 10-100 kDa, and with a degree of substitution in the range of 20-75%. The present disclosure also discloses the bioengineered formulation comprising stem cells, or exosomes, or combinations thereof. Further, the process for preparing the bioengineered formulation is also disclosed therein. Moreover, the formulation comprising: a) exosomes selected from the group consisting of corneal stromal stem cell derived-exosomes, primed mesenchymal stem cell derived-exosomes, and naive mesenchymal stem cell derived-exosomes; and (b) a clinically approved eye drop formulation is also provided.
| # | Name | Date |
|---|---|---|
| 1 | 202247006741-FORM 3 [11-08-2023(online)].pdf | 2023-08-11 |
| 1 | 202247006741.pdf | 2022-02-08 |
| 2 | 202247006741-STATEMENT OF UNDERTAKING (FORM 3) [08-02-2022(online)].pdf | 2022-02-08 |
| 2 | 202247006741-FORM 18 [19-07-2023(online)].pdf | 2023-07-19 |
| 3 | 202247006741-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [08-02-2022(online)].pdf | 2022-02-08 |
| 3 | 202247006741-FORM 3 [03-02-2023(online)].pdf | 2023-02-03 |
| 4 | 202247006741-FORM 1 [08-02-2022(online)].pdf | 2022-02-08 |
| 4 | 202247006741-FORM 3 [04-08-2022(online)].pdf | 2022-08-04 |
| 5 | 202247006741-Proof of Right [07-07-2022(online)].pdf | 2022-07-07 |
| 5 | 202247006741-DRAWINGS [08-02-2022(online)].pdf | 2022-02-08 |
| 6 | 202247006741-FORM-26 [16-03-2022(online)].pdf | 2022-03-16 |
| 6 | 202247006741-DECLARATION OF INVENTORSHIP (FORM 5) [08-02-2022(online)].pdf | 2022-02-08 |
| 7 | 202247006741-COMPLETE SPECIFICATION [08-02-2022(online)].pdf | 2022-02-08 |
| 8 | 202247006741-FORM-26 [16-03-2022(online)].pdf | 2022-03-16 |
| 8 | 202247006741-DECLARATION OF INVENTORSHIP (FORM 5) [08-02-2022(online)].pdf | 2022-02-08 |
| 9 | 202247006741-Proof of Right [07-07-2022(online)].pdf | 2022-07-07 |
| 9 | 202247006741-DRAWINGS [08-02-2022(online)].pdf | 2022-02-08 |
| 10 | 202247006741-FORM 1 [08-02-2022(online)].pdf | 2022-02-08 |
| 10 | 202247006741-FORM 3 [04-08-2022(online)].pdf | 2022-08-04 |
| 11 | 202247006741-FORM 3 [03-02-2023(online)].pdf | 2023-02-03 |
| 11 | 202247006741-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [08-02-2022(online)].pdf | 2022-02-08 |
| 12 | 202247006741-STATEMENT OF UNDERTAKING (FORM 3) [08-02-2022(online)].pdf | 2022-02-08 |
| 12 | 202247006741-FORM 18 [19-07-2023(online)].pdf | 2023-07-19 |
| 13 | 202247006741.pdf | 2022-02-08 |
| 13 | 202247006741-FORM 3 [11-08-2023(online)].pdf | 2023-08-11 |