DESC:FIELD OF THE INVENTION
[0001] The present disclosure relates to a handwash composition. Specifically, the present disclosure provides a handwash concentrate composition comprising an anti-microbial agent, a herbal extract, a moisturizing agent, an anionic surfactant, a solvent and a thickening agent. The present disclosure further provides a process for preparing the handwash concentrate composition.

BACKGROUND OF THE INVENTION
[0002] The background description includes information that may be useful in understanding the present invention. It is not an admission that any of the information provided herein is prior art or relevant to the presently claimed invention, or that any publication specifically or implicitly referenced is prior art.
[0003] Micro-organisms can be found on all surfaces like toilets, kitchen slabs, tables, desktops, vegetables etc. Our body is constantly exposed to these micro-organisms through our hands which keep touching over a million places in a day. Because of the over-exposure of our hands to micro-organisms it is important to maintain their hygiene on a regular basis, especially for health care givers. Using plain water may not ensure complete disinfection as it does not kill the microbes instead just washes away the surface bacteria. Also, water may not be effective in washing away a number of resistant floras from the surface of our hands. Therefore, use of handwashes has become important.
[0004] Researchers overtime have come up with several solutions for handwashes. These solutions started from utilizing chlorine to now using more complex formulations using compounds like chlorhexidine, triclosan and benzalkonium chloride. These compounds are known to be harsh chemicals that may be rough on the skin. These are also dangerous for the environment such that the chemicals flow into water bodies and cause further damage to aquatic life. Other anti-microbials used for hand washing include alcohol-based handwashes. These are capable of killing the pathogenic micro-organisms however it does not have persistent activity. These chemicals are also not environmentally suitable. Further, persistent use of alcohol based washes may irritate the skin and lead to dermatitis. Another problem that these anti-bacterial handwashes face is their limited activity over the range of micro-organisms. Some of these maybe effective for gram-positive and others for gram-negative bacteria, however only a few offer broad-spectrum activity.
[0005] Therefore, there is a need in the art to look for compositions that are gentle on the skin and are broad-spectrum anti-microbials. The composition devised by the inventors of the present disclosure help overcome these drawbacks in the art.

OBJECTS OF THE INVENTION
[0006] An object of the present disclosure is to provide a handwash concentrate composition.
[0007] An object of the present disclosure is to provide a handwash composition that is gentle with cleansing and broad-spectrum anti-microbial properties.
[0008] Another object of the present disclosure is to provide a handwash concentrate composition free of harsh chemicals such as parabens, Methylisothiazolinone, Methylchloroisothiazolinone, cocamidopropyl betaine, triclosan, quaternary ammonium compounds, Benzisothiazolinone, diethanolamine, dioxane, formaldehyde, phthalates, polyethylene glycol, retinyl palmitate and retinol.
[0009] An object of the present disclosure is to provide a handwash concentrate composition that has quick action, is eco-friendly and biodegradable.

SUMMARY OF THE INVENTION
[0010] This summary is provided to introduce a selection of concepts in a simplified form that are further described below in Detailed Description section. This summary is not intended to identify key features or essential features of the claimed subject matter, nor is it intended to be used as an aid in determining the scope of the claimed subject matter.
[0011] The present disclosure relates to a handwash composition. Specifically, the present disclosure provides a handwash concentrate composition having cleansing and anti-microbial properties.
[0012] In one aspect, the present disclosure provides a handwash concentrate composition comprising an anti-microbial agent comprising povidone iodine; a herbal extract comprising neem extract, tulsi extract, or their combination; an anionic surfactant; a thickening agent, a solvent and a moisturizing agent.
[0013] In an embodiment, the surfactant may be selected from sodium lauryl sulfate, triethanolamine lauryl sulphate, ammonium lauryl sulfate, sodium laureth sulfate, sodium lauryl sarcosinate, sodium myreth sulfate, sodium pareth sulfate, sodium stearte, a olefin sulfonate, and ammonium laureth sulfate or combinations thereof.
[0014] In an embodiment, the thickening agent may be selected from hydroxypropyl methylcellulose, xanthan gum, guar gum, sodium starch glycolate, polyethylene glycol, polyvinyl pyrrolidone, methyl cellulose or combinations thereof.
[0015] In an embodiment, the moisturizing agent may be selected from aloe vera gel, polyethylene glycol, propylene glycol, jojoba oil or combinations thereof.
[0016] In an embodiment, the solvent may be glycerol, polyethylene glycol, propylene glycol, or combinations thereof.
[0017] In an embodiment, the composition further comprises one or more additive(s). In an embodiment, the additive may be selected from fragrance, coloring agent, preservative, pH regulator, fillers or combinations thereof.
[0018] In an embodiment, the coloring agent may be selected from dyes of orange color, yellow color, blue color, red color, purple color, or other permitted colors.
[0019] In an embodiment, the preservative may be selected from tetrasodium EDTA, citric acid, sodium benzoate or combinations thereof.
[0020] In another aspect, the present disclosure provides a handwash concentrate formulation comprising an anti-microbial agent comprising povidone iodine; a herbal extract comprising neem extract, tulsi extract, or their combination; an anionic surfactant; a thickening agent; a solvent, a moisturizing agent; and one or more additive(s).
[0021] In another aspect, the present disclosure provides a process for preparing the handwash concentrate composition, wherein the process comprises the steps of: (a) mixing liquid components of the composition in a solvent till homogenous to give a pre-mixture A; (b) grinding and mixing solid components of the composition till homogenous to give pre-mixture B; and (c) blending the pre-mixture A and pre-mixture B by stirring till uniform homogenous composition is obtained; wherein the composition comprises an anti-microbial agent comprising povidone iodine; a herbal extract comprising neem extract, tulsi extract, or their combination; an anionic surfactant; a thickening agent, a solvent and a moisturizing agent.
[0022] Various objects, features, aspects and advantages of the inventive subject matter will become more apparent from the following detailed description of preferred embodiments.

DETAILED DESCRIPTION
[0023] Unless the context requires otherwise, throughout the specification and claims which follow, the word “comprise” and variations thereof, such as, “comprises” and “comprising” are to be construed in an open, inclusive sense that is as “including, but not limited to.”
[0024] Reference throughout this specification to “one embodiment” or “an embodiment” means that a particular feature, structure or characteristic described in connection with the embodiment is included in at least one embodiment. Thus, the appearances of the phrases “in one embodiment” or “in an embodiment” in various places throughout this specification are not necessarily all referring to the same embodiment. Furthermore, the particular features, structures, or characteristics may be combined in any suitable manner in one or more embodiments.
[0025] As used in this specification and the appended claims, the singular forms “a,” “an,” and “the” include plural referents unless the content clearly dictates otherwise. It should also be noted that the term “or” is generally employed in its sense including “and/or” unless the content clearly dictates otherwise.
[0026] In some embodiments, the numbers expressing quantities of ingredients, properties such as concentration, reaction conditions, and so forth, used to describe and claim certain embodiments of the invention are to be understood as being modified in some instances by the term “about.” Accordingly, in some embodiments, the numerical parameters set forth in the written description are approximations that can vary depending upon the desired properties sought to be obtained by a particular embodiment. In some embodiments, the numerical parameters should be construed in light of the number of reported significant digits and by applying ordinary rounding techniques. Notwithstanding that the numerical ranges and parameters setting forth the broad scope of some embodiments of the invention are approximations, the numerical values set forth in the specific examples are reported as precisely as practicable.
[0027] The recitation of ranges of values herein is merely intended to serve as a shorthand method of referring individually to each separate value falling within the range. Unless otherwise indicated herein, each individual value is incorporated into the specification as if it were individually recited herein. All methods described herein can be performed in any suitable order unless otherwise indicated herein or otherwise clearly contradicted by context. The use of any and all examples, or exemplary language (e.g. “such as”) provided with respect to certain embodiments herein is intended merely to better illuminate the invention and does not pose a limitation on the scope of the invention otherwise claimed. No language in the specification should be construed as indicating any non-claimed element essential to the practice of the invention.
[0028] The headings and abstract of the invention provided herein are for convenience only and do not interpret the scope or meaning of the embodiments.
[0029] The following discussion provides many example embodiments of the inventive subject matter. Although each embodiment represents a single combination of inventive elements, the inventive subject matter is considered to include all possible combinations of the disclosed elements. Thus if one embodiment comprises elements A, B, and C, and a second embodiment comprises elements B and D, then the inventive subject matter is also considered to include other remaining combinations of A, B, C, or D, even if not explicitly disclosed.
[0030] The present disclosure relates to a handwash concentrate composition. Specifically, the present disclosure provides a handwash concentrate composition having cleansing and disinfectant properties.
[0031] In an embodiment, the present disclosure provides a handwash concentrate composition comprising an anti-microbial agent comprising povidone iodine; a herbal extract comprising neem extract, tulsi extract, or their combination; an anionic surfactant; a thickening agent, a solvent and a moisturizing agent.
[0032] In an embodiment, the anti-microbial agent may be present in a range of about 0.1% w/w to about 1.0%w/w, preferably about 0.3%w/w to about 0.6%w/w of the composition.
[0033] In an embodiment, the herbal extract may be present in a range of about 0.01% w/w to about 1.0%w/w, preferably about 0.03%w/w to about 0.7%w/w of the composition.
[0034] In the present handwash concentrate composition the active ingredient povidone iodine synergistically works with the herbal extracts of neem & tulsi to give an enhanced anti-microbial effect.
[0035] In an embodiment, the surfactant may be selected from sodium lauryl sulfate, triethanolamine lauryl sulphate, ammonium lauryl sulfate, sodium laureth sulfate, sodium lauryl sarcosinate, sodium myreth sulfate, sodium pareth sulfate, sodium stearte, a olefin sulfonate, and ammonium laureth sulfate, or combinations thereof.
[0036] In an embodiment, the surfactant may be present in a range of about 10% w/w to about 30%w/w, preferably about 11%w/w to about 27%w/w of the composition.
[0037] In an embodiment, the thickening agent may be selected from hydroxypropyl methylcellulose, xanthan gum, guar gum, sodium starch glycolate, polyethylene glycol, polyvinyl pyrrolidone, methyl cellulose or combinations thereof.
[0038] In an embodiment, the thickening agent may be present in a range of about 0.5% w/w to about 15.0%w/w, preferably about 1%w/w to about 12%w/w of the composition.
[0039] In an embodiment, the moisturizing agent may be selected from aloe vera gel, propylene glycol, glycerol, jojoba oil or combinations thereof.
[0040] In an embodiment, the moisturizing agent may be present in a range of about 0.01% w/w to about 0.1%w/w, preferably about 0.03%w/w to about 0.05%w/w of the composition.
[0041] In an embodiment, the solvent may be glycerol, polyethylene glycol, propylene glycol, or combinations thereof.
[0042] In an embodiment, the solvent may be present in a range of about 40% w/w to about 55%w/w, preferably about 44%w/w to about 50%w/w of the composition.
[0043] In an embodiment, the composition further comprises one or more additive(s). In an embodiment, the additive may be selected from fragrance, coloring agent, preservative, pH regulator, fillers or combinations thereof. However, a person of skill in the art would understand that any other additive(s) well-known in the art may be employed without going beyond the spirit and scope of the present disclosure.
[0044] In an embodiment, the additive(s) may be present in a range of about 0.001% w/w to about 10%w/w, preferably about 0.005%w/w to about 5%w/w of the composition.
[0045] In an embodiment, the coloring agent may be selected from dyes of orange color, yellow color, blue color, red color, purple color, red sandalwood powder, yellow sandalwood powder, rose hips powder brown color, rose pink color or other permitted colors.
[0046] In an embodiment, the preservative may be selected from tetrasodium EDTA, citric acid, sodium benzoate or combinations thereof.
[0047] In an embodiment, the fragrance may be selected from orange, lavender, hibiscus, cherry blossom, winter cherry, rose, menthol, lemon, or combinations thereof.
[0048] In an embodiment, the pH regulator may be selected from sodium hydroxide, potassium hydroxide, acetic acid and citric acid.
[0049] In a preferred embodiment, the present disclosure provides a handwash concentrate composition comprising glycerol, aloe vera gel, triethanolamine lauryl sulfate (TLS), sodium lauryl sulfate (SLS), xanthan gum, tetrasodium EDTA, hydroxypropyl methylcellulose, povidone iodine, neem extract and tulsi extract.
[0050] In another embodiment, the present disclosure provides a handwash concentrate formulation comprising an anti-microbial agent comprising povidone iodine; a herbal extract comprising neem extract, tulsi extract, or their combination; an anionic surfactant; a thickening agent; a solvent, a moisturizing agent; and one or more additive(s).
[0051] In an embodiment, the composition of the present disclosure can be easily converted into a ready-to-use formulation. The composition can be dissolved in water to give the ready-to-use formulation.
[0052] In an embodiment, the composition has effective cleaning and strong anti-microbial activity. In an embodiment, the composition has a broad-spectrum anti-microbial activity, including bacteria such as gram positive and gram negative bacteria; viruses; bacterial spores; and fungi. In a specific embodiment, the composition is effective against Candida albicans, Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Salmonella abony, Aspergillus brasilensis, and Listeria monocytogenes.
[0053] In some embodiments, the composition shows up to 99.99% anti-microbial efficacy.
[0054] In an embodiment, the composition provides quick action against microbes. In some embodiments, the action may be noticed within 20 seconds of exposure.
[0055] Despite its strong anti-microbial effect the composition is soft on human skin and provides excellent skin moisturization and reduces any dryness caused by surfactant. The composition is gentle and avoids use of harsh chemicals including parabens, methylisothiazolinone (MIT), methylchloroisothiazolinone (CMIT), cocamidopropyl betaine (CAPB), triclosan, Quaternary ammonium compounds (QUATs), BIT, diethanolamine, dioxane, formaldehyde, phthalates, polyethylene glycol (PEG compounds), retinyl palmitate and retinol (Vitamin A).
[0056] In an embodiment, the composition is biodegradable and eco-friendly.
[0057] In an embodiment of the present disclosure, the composition works synergistically to give enhanced stability and storage capability. In some embodiments, the composition may have a shelf life of over 24 months.
[0058] In an embodiment, the composition forms a viscous solution in water. In some embodiments, about 25 mL of the composition in about 500mL water may give a ready-to-use formulation having a viscosity in range of about 100 centipoise (cps) to about 3000 cps, preferably about 700-800 cps.
[0059] In an embodiment, the composition has pH in the range of about 5-7.5; specific density of about 1.0 to about 1.2.
[0060] The handwash concentrate composition may be employed in kitchens, hospitals, toilets, public washrooms or urinals, gyms, restaurants, clinics, health centers, transport vehicles, rails, shopping centers, or any other place where humans come in contact with microbes or the risk of exposure to fomites is high.
[0061] The composition exists as a concentrate, thus decreasing the overall use of plastic per person and is relatively cost-effective than the existing products. The existing hand wash compositions are available as single use plastic bottles, resulting in around 540 - 600 grams of single use plastic per person per year that can be saved by the use of the composition of the present disclosure. In a preferred embodiment, the composition exists as a concentrate sachet that can be dissolved in a reusable bottle before use resulting in reduction of the use of multiple single use plastic bottles every month.
[0062] In another embodiment, the present disclosure provides a process for preparing a handwash concentrate composition, wherein the process comprises the steps of: (a) mixing liquid components of the composition in a solvent till homogenous to give a pre-mixture A; (b) grinding and mixing solid components of the composition till homogenous to give pre-mixture B; and (c) blending the pre-mixture A and pre-mixture B by stirring till uniform homogenous composition is obtained; wherein the composition comprises an anti-microbial agent comprising povidone iodine; a herbal extract comprising neem extract, tulsi extract, or their combination; an anionic surfactant; a thickening agent, a solvent and a moisturizing agent.
[0063] While the foregoing describes various embodiments of the disclosure, other and further embodiments of the disclosure may be devised without departing from the basic scope thereof. The scope of the invention is determined by the claims that follow. The invention is not limited to the described embodiments, versions or examples, which are included to enable a person having ordinary skill in the art to make and use the invention when combined with information and knowledge available to the person having ordinary skill in the art.
EXAMPLES
[0064] The disclosure will now be illustrated with working examples, which is intended to illustrate the working of disclosure and not intended to take restrictively to imply any limitations on the scope of the present disclosure. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood to one of ordinary skill in the art to which this disclosure belongs. Although methods and materials similar or equivalent to those described herein can be used in the practice of the disclosed methods and compositions, the exemplary methods, devices and materials are described herein. It is to be understood that this disclosure is not limited to particular methods, and experimental conditions described, as such methods and conditions may vary.
Materials: All raw materials were in house (IH) grades and commercially purchased from third party manufacturers.
Example 1
Handwash concentrate composition
[0065] The concentrate composition was prepared as per proportions provided in Table No. 1 below. For pre-mixture A, HPMC and xanthan Gum were added in a clean and oven dried beaker, to which glycerol was added and mixed with a stirring rod or in a homogenizer till uniformity was achieved. TLS was added to this beaker and mixed with stirring rod/homogenizer till uniformity was achieved. This was followed by addition of aloe vera gel with mixing. For pre-mixture B, SLS, PVP-I, EDTA, coloring agent, neem and tulsi extracts were taken in another clean and oven-dried beaker and ground by crushing till uniformity was achieved. Pre-mixtures A and B were mixed together using a stirring road or homogenizer till uniformity was achieved. Fragrance was added and mixed to give the composition (an orange viscous gel). The composition had pH in the range of 5.0-7.5 and specific density in the range 1.0-1.2. The composition was kept tightly closed (avoiding air contact) at room temperature till further use.
Table No. 1: Handwash concentrate composition
S. No. Ingredients Name Composition
(% w/w) Functions
1. Glycerol 44 Solvent
2. Triethanolamine Lauryl Sulfate (TLS) 26 Anionic Surfactant
3. Sodium Lauryl Sulfate (SLS) 12 Anionic Surfactant
4. Xanthan Gum 12 Thickening Agent
5. Fragrance Nagpur Orange 2 Fragrance
6. Tetrasodium EDTA 1.68 Preservative
7. Hydroxypropyl Methylcellulose (HPMC) 1 Thickening Agent
8. Color 0.80 Coloring Agent
9. Povidone iodine (PVP-I) 0.4 Antimicrobial Agent
10. Neem Extract 0.04 Herbal Extract
11. Tulsi Extract 0.04 Herbal Extract
12. Aloe Vera Gel 0.04 Moisturizing Agent
Total 100

Example 2
Anti-microbial activity
[0066] The composition of Example 1 was tested for its anti-microbial activity by a time kill assay. The assay notes the changes in the microbial population within a specified time in presence of the composition. The time kill assays were performed on the ready-to-use formulation. The ready-to-use formulations were prepared after dilution of 25ml of the concentrate composition of Example 1 in 500 mL of water. The assays were performed as per the American Standard for Testing and Material protocol ASTM-E2315-16.
[0067] Method:
[0068] TEST PROCEDURE- The working cultures of the test organisms were prepared. 10 mL of the sample was taken with respect to individual test culture.100 µL of adjusted test cultures were inoculated in individual samples prepared. A contact time of 20-60 seconds was considered. Using the pour plate technique 1 mL of the formulation was pipetted to triplicated petri dishes for each dilution prepared by serial dilution technique and then 20mL of melted SCDA was added. The petri dish was incubated at 30-35°C for 72 hours. The colonies on the petri dishes were counted with the help of colony counter after incubation and the observations were recorded in cfu (colony forming unit).
[0069] Note- The petri dish showing a number of colonies included in a 15-300 for bacterial and fungal of 15-150 range to be used to perform the result calculation.
LOG REDUCTION CALCULATION
[0070] The effectiveness of the disinfection procedure against each challenge organism was calculated for each product as a log10 reduction as follows:
Log10 Reduction per product = Log10 [Positive Control Count] – Log10 [Test Surface Count]
Note: The log reduction was rounded to the nearest 0.1 value.
[0071] For each product concentration and each experimental condition, calculated and recorded the decimal log reduction separately.
ACCEPTANCE CRITERIA
[0072] In case of surface challenge test positive control should yield 50 to 200% recovery of the microorganism in comparison to inoculums added. Bactericidal, fungicidal or yeasticidal activity on surfaces for general purposes is characterized by the concentration of the tested product. Agents should demonstrate a 3 log reduction of vegetative test organisms and mold spores.
[0073] Results: The results of the test are provided in Table No. 2 below:

Table No. 2: Anti-microbial activity of the composition
S. No. Organism Contact time
(sec) % reduction
1 Candida L albicans(MTCC 227) 20 99.99%
30 99.99%
60 99.99%
2 S. aureus (ATCC 6538) 20 99.99%
30 99.99%
60 99.99%
3 Staph. Epidermis (ATCC12228) 20 99.99%
30 99.99%
60 99.99%
4 Escherichia coli (ATCC 8739) 20 99.99%
30 99.99%
60 99.99%
5 Salmonella abony (NCTC6017) 20 99.99%
30 99.99%
60 99.99%
6 Aspergillus brasilensis (ATCC16404) 20 99.99%
30 99.99%
60 99.99%
7 Lisleria monocytogenes (ATCC 19111) 20 99.99%
30 99.99%
60 99.99%

[0074] Thus, the composition of the present disclosure provides quick action as the anti-microbial efficacy was about 99.99% within 20 seconds of use. Additionally, the composition shows broad spectrum activity.

EXAMPLE 3
Disk-diffusion test
[0075] The disinfectant activity of povidone-iodine was significantly increased by neem and tulsi extract in the ready-to-use formulation in the specific weight percentage ranges. To study this, a disk diffusion test was performed on E. Coli using the composition of Example 1 and some comparative compositions as shown in Table No. 3 below.
Table No. 3: Disk-diffusion tests
S. No Component Antimicrobial Inhibition Zone (cm)
1. Povidone Iodine (0.033%) 2.8
2. Povidone Iodine (0.033%)+Neem Extract(0.003%) 3.4
3. Povidone Iodine(0.033%)+Tulsi Extract(0.003%) 3.4
4. Povidone Iodine(0.033%)+Neem Extract(0.003%)+Tulsi Extract(0.003%) 4.0

[0076] From the results, it was noted that the combination of povidone iodine, neem extract and tulsi extract mutually regulate the antimicrobial activity.
[0077] From the foregoing, it will be appreciated that, although specific embodiments of the invention have been described herein merely for purposes of illustration, various modifications may be made without deviating from the spirit and scope of the invention and should not be construed so as to limit the scope of the invention or the appended claims in any way.

ADVANTAGES OF THE PRESENT INVENTION
[0078] The present disclosure provides a composition that overcomes the deficiencies of the prior art.

[0079] The present disclosure provides a handwash concentrate composition that is a broad spectrum anti-microbial and is devoid of harsh chemicals.
[0080] The present disclosure provides a handwash composition that is gentle on the hands of the user, is eco-friendly and biodegradable.

CLAIMS:1. A handwash concentrate composition comprising an anti-microbial agent comprising povidone iodine; a herbal extract comprising neem extract, tulsi extract, or their combination; an anionic surfactant; a thickening agent, a solvent and a moisturizing agent.
2. The composition as claimed in claim 1, wherein the anti-microbial agent is present in a range of 0.1% w/w to 1.0%w/w of the composition.
3. The composition as claimed in claim 1, wherein the herbal extract is present in a range of 0.01% w/w to 1.0%w/w of the composition.
4. The composition as claimed in claim 1, wherein the surfactant is selected from sodium lauryl sulfate, triethanolamine lauryl sulphate, ammonium lauryl sulfate, sodium laureth sulfate, sodium lauryl sarcosinate, sodium myreth sulfate, sodium pareth sulfate, sodium stearte, a olefin sulfonate, and ammonium laureth sulfate or combinations thereof.
5. The composition as claimed in claim 1, wherein the surfactant is present in a range of 10% w/w to 30%w/w of the composition.
6. The composition as claimed in claim 1, wherein the thickening agent is selected from hydroxypropyl methylcellulose, xanthan gum, guar gum, sodium starch glycolate, polyethylene glycol, polyvinyl pyrrolidone, methyl cellulose or combinations thereof.
7. The composition as claimed in claim 1, wherein the thickening agent is present in a range of 0.5% w/w to 15.0%w/w of the composition.
8. The composition as claimed in claim 1, wherein the moisturizing agent is selected from aloe vera gel, propylene glycol, propylene glycol, jojoba oil or combinations thereof.
9. The composition as claimed in claim 1, wherein the moisturizing agent is present in a range of 0.01% w/w to 0.1%w/w of the composition.
10. The composition as claimed in claim 1, wherein the solvent is glycerol, polyethylene glycol, propylene glycol, or combinations thereof.
11. The composition as claimed in claim 1, wherein the solvent is present in a range of 40% w/w to 55%w/w of the composition.
12. The composition as claimed in claim 1, wherein the composition further comprises one or more additive(s).
13. A handwash concentrate formulation comprising an anti-microbial agent comprising povidone iodine; a herbal extract comprising neem extract, tulsi extract, or their combination; an anionic surfactant; a thickening agent; a solvent; a moisturizing agent; and one or more additive(s).
14. A process for preparing a handwash concentrate composition, wherein the process comprises the steps of: (a) mixing liquid components of the composition in a solvent till homogenous to give a pre-mixture A; (b) grinding and mixing solid components of the composition till homogenous to give pre-mixture B; and (c) blending the pre-mixture A and pre-mixture B by stirring till uniform homogenous composition is obtained; wherein the composition comprises an anti-microbial agent comprising povidone iodine; a herbal extract comprising neem extract, tulsi extract, or their combination; an anionic surfactant; a solvent; a thickening agent and a moisturizing agent.