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Immunochemical Detection Of Single Target Entities

Abstract: The present invention relates to immunochemical visualization and quantification of single target entities, such as single molecules, single molecular structures, single particles, etc. in samples wherein said single entities are immobilized. In particular, the invention relates to methods for visualization and quantification of single units of biological or chemical targets, in particular to immunochemical visualization of single molecules of biological targets in histological samples. The methods of the invention comprise a step of forming discrete deposits of detectable molecules at single target sites of sample mediated by an enzyme with oxydoreductase activity, wherein a single target site comprises a single unit of a target. The invention also relates to assays comprising the present visualization and quantification methods and diagnostic applications of said methods. The methods employ reporter deposit techniques (card) and at least two different substrates, one of which is a water so luttes conjugate comprising two compounds capable of serving as substrates of the enzyme and a detectable label.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
14 May 2012
Publication Number
06/2014
Publication Type
INA
Invention Field
PHYSICS
Status
Email
Parent Application
Patent Number
Legal Status
Grant Date
2019-08-20
Renewal Date

Applicants

DAKO DENMARK A/S
PRODUKTIONSVEJ 42, DK-2600 GLOSTRUP.

Inventors

1. LOHSE, JESPER
MELISSEHAVEN 23, 3.TH, DK-2730 HERLEV.

Specification

Documents

Application Documents

# Name Date
1 4247-CHENP-2012 ABSTRACT 14-05-2012.pdf 2012-05-14
1 4247-CHENP-2012-IntimationOfGrant20-08-2019.pdf 2019-08-20
2 4247-CHENP-2012 POWER OF ATTORNEY 14-05-2012.pdf 2012-05-14
2 4247-CHENP-2012-PatentCertificate20-08-2019.pdf 2019-08-20
3 Abstract_Granted 318464_20-08-2019.pdf 2019-08-20
3 4247-CHENP-2012 PCT 14-05-2012.pdf 2012-05-14
4 Claims_Granted 318464_20-08-2019.pdf 2019-08-20
4 4247-CHENP-2012 FORM-5 14-05-2012.pdf 2012-05-14
5 Description_Granted 318464_20-08-2019.pdf 2019-08-20
5 4247-CHENP-2012 FORM-3 14-05-2012.pdf 2012-05-14
6 Drawings_Granted 318464_20-08-2019.pdf 2019-08-20
6 4247-CHENP-2012 FORM-2 14-05-2012.pdf 2012-05-14
7 Marked up Claims_Granted 318464_20-08-2019.pdf 2019-08-20
7 4247-CHENP-2012 FORM-1 14-05-2012.pdf 2012-05-14
8 4247-CHENP-2012-ABSTRACT [07-09-2018(online)].pdf 2018-09-07
8 4247-CHENP-2012 DRAWINGS 14-05-2012.pdf 2012-05-14
9 4247-CHENP-2012 DESCRIPTION (COMPLETE) 14-05-2012.pdf 2012-05-14
9 4247-CHENP-2012-CLAIMS [07-09-2018(online)].pdf 2018-09-07
10 4247-CHENP-2012 CORRESPONDENCE OTHERS 14-05-2012.pdf 2012-05-14
10 4247-CHENP-2012-COMPLETE SPECIFICATION [07-09-2018(online)].pdf 2018-09-07
11 4247-CHENP-2012 CLAIMS 14-05-2012.pdf 2012-05-14
11 4247-CHENP-2012-DRAWING [07-09-2018(online)].pdf 2018-09-07
12 4247-CHENP-2012 ABSTRACT 14-05-2012.pdf 2012-05-14
12 4247-CHENP-2012-FER_SER_REPLY [07-09-2018(online)].pdf 2018-09-07
13 4247-CHENP-2012 FORM-3 12-11-2012.pdf 2012-11-12
13 4247-CHENP-2012-FER.pdf 2018-05-31
14 4247-CHENP-2012 FORM-1 12-11-2012.pdf 2012-11-12
14 4247-CHENP-2012-Correspondence-PA-211215.pdf 2016-06-13
15 4247-CHENP-2012 CORRESPONDENCE OTHERS 12-11-2012.pdf 2012-11-12
15 4247-CHENP-2012-Power of Attorney-211215.pdf 2016-06-13
16 4247-CHENP-2012 CORRESPONDENCE OTHERS 10-04-2015.pdf 2015-04-10
16 4247-CHENP-2012 FORM-18 23-09-2013.pdf 2013-09-23
17 4247-CHENP-2012 FORM-13 10-04-2015.pdf 2015-04-10
17 4247-CHENP-2012 CORRESPONDENCE OTHERS 23-09-2013.pdf 2013-09-23
18 4247-CHENP-2012 AMENDED CLAIMS 23-09-2013.pdf 2013-09-23
18 4247-CHENP-2012 POWER OF ATTORNEY 10-04-2015.pdf 2015-04-10
19 2015-03-12 Form 1.pdf 2015-03-12
19 4247-CHENP-2012 FORM-13 23-09-2013.pdf 2013-09-23
20 2015-03-12 Form 13.pdf 2015-03-12
20 4247-CHENP-2012 FORM-3 26-09-2013.pdf 2013-09-26
21 2015-03-12 form-26 - Power of Attorney.pdf 2015-03-12
21 4247-CHENP-2012 CORRESPONDENCE OTHERS 26-09-2013.pdf 2013-09-26
22 4247-CHENP-2012 FORM-13 12-03-2015.pdf 2015-03-12
23 2015-03-12 form-26 - Power of Attorney.pdf 2015-03-12
23 4247-CHENP-2012 CORRESPONDENCE OTHERS 26-09-2013.pdf 2013-09-26
24 4247-CHENP-2012 FORM-3 26-09-2013.pdf 2013-09-26
24 2015-03-12 Form 13.pdf 2015-03-12
25 4247-CHENP-2012 FORM-13 23-09-2013.pdf 2013-09-23
25 2015-03-12 Form 1.pdf 2015-03-12
26 4247-CHENP-2012 AMENDED CLAIMS 23-09-2013.pdf 2013-09-23
26 4247-CHENP-2012 POWER OF ATTORNEY 10-04-2015.pdf 2015-04-10
27 4247-CHENP-2012 CORRESPONDENCE OTHERS 23-09-2013.pdf 2013-09-23
27 4247-CHENP-2012 FORM-13 10-04-2015.pdf 2015-04-10
28 4247-CHENP-2012 CORRESPONDENCE OTHERS 10-04-2015.pdf 2015-04-10
28 4247-CHENP-2012 FORM-18 23-09-2013.pdf 2013-09-23
29 4247-CHENP-2012 CORRESPONDENCE OTHERS 12-11-2012.pdf 2012-11-12
29 4247-CHENP-2012-Power of Attorney-211215.pdf 2016-06-13
30 4247-CHENP-2012 FORM-1 12-11-2012.pdf 2012-11-12
30 4247-CHENP-2012-Correspondence-PA-211215.pdf 2016-06-13
31 4247-CHENP-2012 FORM-3 12-11-2012.pdf 2012-11-12
31 4247-CHENP-2012-FER.pdf 2018-05-31
32 4247-CHENP-2012 ABSTRACT 14-05-2012.pdf 2012-05-14
32 4247-CHENP-2012-FER_SER_REPLY [07-09-2018(online)].pdf 2018-09-07
33 4247-CHENP-2012 CLAIMS 14-05-2012.pdf 2012-05-14
33 4247-CHENP-2012-DRAWING [07-09-2018(online)].pdf 2018-09-07
34 4247-CHENP-2012 CORRESPONDENCE OTHERS 14-05-2012.pdf 2012-05-14
34 4247-CHENP-2012-COMPLETE SPECIFICATION [07-09-2018(online)].pdf 2018-09-07
35 4247-CHENP-2012 DESCRIPTION (COMPLETE) 14-05-2012.pdf 2012-05-14
35 4247-CHENP-2012-CLAIMS [07-09-2018(online)].pdf 2018-09-07
36 4247-CHENP-2012-ABSTRACT [07-09-2018(online)].pdf 2018-09-07
36 4247-CHENP-2012 DRAWINGS 14-05-2012.pdf 2012-05-14
37 Marked up Claims_Granted 318464_20-08-2019.pdf 2019-08-20
37 4247-CHENP-2012 FORM-1 14-05-2012.pdf 2012-05-14
38 Drawings_Granted 318464_20-08-2019.pdf 2019-08-20
38 4247-CHENP-2012 FORM-2 14-05-2012.pdf 2012-05-14
39 Description_Granted 318464_20-08-2019.pdf 2019-08-20
39 4247-CHENP-2012 FORM-3 14-05-2012.pdf 2012-05-14
40 Claims_Granted 318464_20-08-2019.pdf 2019-08-20
40 4247-CHENP-2012 FORM-5 14-05-2012.pdf 2012-05-14
41 Abstract_Granted 318464_20-08-2019.pdf 2019-08-20
41 4247-CHENP-2012 PCT 14-05-2012.pdf 2012-05-14
42 4247-CHENP-2012 POWER OF ATTORNEY 14-05-2012.pdf 2012-05-14
42 4247-CHENP-2012-PatentCertificate20-08-2019.pdf 2019-08-20
43 4247-CHENP-2012 ABSTRACT 14-05-2012.pdf 2012-05-14
43 4247-CHENP-2012-IntimationOfGrant20-08-2019.pdf 2019-08-20

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1 sr_30-05-2018.pdf

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