Abstract: A method for the prediction of adverse cross-reactions between lead candidate biomolecules and potential reactant molecules, often biopolymers, is described. In a computational system, reactions are modeled within a suitable environment, in order to determine a reaction profile between a lead candidate molecule and a potential reactant molecule. A risk assessment is then generated for each lead based on a plurality of reaction profiles for the lead with respect to a plurality of potential reactant molecules. The method includes provisions for redesign and optimization of the lead candidate, possibly iterative in nature, in order to avoid predicted adverse cross-reactions.
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| Section | Controller | Decision Date |
|---|---|---|
| # | Name | Date |
|---|---|---|
| 1 | 1665-CHENP-2006 CORRESPONDENCE OTHERS 13-06-2011.pdf | 2011-06-13 |
| 1 | Correspondence by Agent_Power of Attorney_26-04-2017.pdf | 2017-04-26 |
| 2 | 1665-chenp-2006-pct.pdf | 2011-09-03 |
| 2 | Form 26 [25-04-2017(online)].pdf | 2017-04-25 |
| 3 | Other Patent Document [25-04-2017(online)].pdf | 2017-04-25 |
| 3 | 1665-chenp-2006-form 5.pdf | 2011-09-03 |
| 4 | Other Patent Document [07-04-2017(online)].pdf | 2017-04-07 |
| 4 | 1665-chenp-2006-form 3.pdf | 2011-09-03 |
| 5 | 1665-CHENP-2006_EXAMREPORT.pdf | 2016-07-02 |
| 5 | 1665-chenp-2006-form 1.pdf | 2011-09-03 |
| 6 | 1665-chenp-2006-drawings.pdf | 2011-09-03 |
| 6 | 1665-CHENP-2006 AMENDED CLAIMS. 14-08-2012.pdf | 2012-08-14 |
| 7 | 1665-chenp-2006-description(complete).pdf | 2011-09-03 |
| 7 | 1665-CHENP-2006 AMENDED PAGES OF SPECIFICATION 14-08-2012.pdf | 2012-08-14 |
| 8 | 1665-chenp-2006-correspondnece-others.pdf | 2011-09-03 |
| 8 | 1665-CHENP-2006 CORRESPONDENCE OTHERS. 14-08-2012.pdf | 2012-08-14 |
| 9 | 1665-CHENP-2006 CORRESPONDENCE OTHERS 10-08-2012.pdf | 2012-08-10 |
| 9 | 1665-chenp-2006-claims.pdf | 2011-09-03 |
| 10 | 1665-CHENP-2006 CORRESPONDENCE OTHERS 26-07-2012.pdf | 2012-07-26 |
| 10 | 1665-chenp-2006-abstract.pdf | 2011-09-03 |
| 11 | 1665-CHENP-2006 POWER OF ATTORNEY 09-01-2012.pdf | 2012-01-09 |
| 11 | 1665-CHENP-2006 CORRESPONDENCE OTHERS 10-07-2012.pdf | 2012-07-10 |
| 12 | 1665-CHENP-2006 OTHER PATENT DOCUMENT 11-01-2012.pdf | 2012-01-11 |
| 12 | 1665-CHENP-2006 OTHER PATENT DOCUMENT 09-01-2012.pdf | 2012-01-09 |
| 13 | 1665-CHENP-2006 FORM-3 09-01-2012.pdf | 2012-01-09 |
| 13 | 1665-CHENP-2006 CORRESPONDENCE OTHERS 11-01-2012.pdf | 2012-01-11 |
| 14 | 1665-CHENP-2006 AMENDED PAGES OF SPECIFICATION 09-01-2012.pdf | 2012-01-09 |
| 14 | 1665-CHENP-2006 EXAMINATION REPORT REPLY RECEIVED 09-01-2012.pdf | 2012-01-09 |
| 15 | 1665-CHENP-2006 AMENDED .CLAIMS 09-01-2012.pdf | 2012-01-09 |
| 16 | 1665-CHENP-2006 AMENDED PAGES OF SPECIFICATION 09-01-2012.pdf | 2012-01-09 |
| 16 | 1665-CHENP-2006 EXAMINATION REPORT REPLY RECEIVED 09-01-2012.pdf | 2012-01-09 |
| 17 | 1665-CHENP-2006 CORRESPONDENCE OTHERS 11-01-2012.pdf | 2012-01-11 |
| 17 | 1665-CHENP-2006 FORM-3 09-01-2012.pdf | 2012-01-09 |
| 18 | 1665-CHENP-2006 OTHER PATENT DOCUMENT 09-01-2012.pdf | 2012-01-09 |
| 18 | 1665-CHENP-2006 OTHER PATENT DOCUMENT 11-01-2012.pdf | 2012-01-11 |
| 19 | 1665-CHENP-2006 POWER OF ATTORNEY 09-01-2012.pdf | 2012-01-09 |
| 19 | 1665-CHENP-2006 CORRESPONDENCE OTHERS 10-07-2012.pdf | 2012-07-10 |
| 20 | 1665-CHENP-2006 CORRESPONDENCE OTHERS 26-07-2012.pdf | 2012-07-26 |
| 20 | 1665-chenp-2006-abstract.pdf | 2011-09-03 |
| 21 | 1665-CHENP-2006 CORRESPONDENCE OTHERS 10-08-2012.pdf | 2012-08-10 |
| 21 | 1665-chenp-2006-claims.pdf | 2011-09-03 |
| 22 | 1665-CHENP-2006 CORRESPONDENCE OTHERS. 14-08-2012.pdf | 2012-08-14 |
| 22 | 1665-chenp-2006-correspondnece-others.pdf | 2011-09-03 |
| 23 | 1665-CHENP-2006 AMENDED PAGES OF SPECIFICATION 14-08-2012.pdf | 2012-08-14 |
| 23 | 1665-chenp-2006-description(complete).pdf | 2011-09-03 |
| 24 | 1665-CHENP-2006 AMENDED CLAIMS. 14-08-2012.pdf | 2012-08-14 |
| 24 | 1665-chenp-2006-drawings.pdf | 2011-09-03 |
| 25 | 1665-CHENP-2006_EXAMREPORT.pdf | 2016-07-02 |
| 25 | 1665-chenp-2006-form 1.pdf | 2011-09-03 |
| 26 | Other Patent Document [07-04-2017(online)].pdf | 2017-04-07 |
| 26 | 1665-chenp-2006-form 3.pdf | 2011-09-03 |
| 27 | Other Patent Document [25-04-2017(online)].pdf | 2017-04-25 |
| 27 | 1665-chenp-2006-form 5.pdf | 2011-09-03 |
| 28 | Form 26 [25-04-2017(online)].pdf | 2017-04-25 |
| 28 | 1665-chenp-2006-pct.pdf | 2011-09-03 |
| 29 | Correspondence by Agent_Power of Attorney_26-04-2017.pdf | 2017-04-26 |
| 29 | 1665-CHENP-2006 CORRESPONDENCE OTHERS 13-06-2011.pdf | 2011-06-13 |