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"Lyophilized Formulations For Small Modular Immunopharmaceuticals"

Abstract: The present invention provides, among other things, stable formulations for small modular immunopharmaceutical (SMIP™) proteins. In some embodiments, the present invention provides a formulation containing a lyophilized mixture of a small modular immunopharmaceutical protein, wherein less than 7% of the lyophilized small modular immunopharmaceutical protein exists in aggregated form. Formulations according to the invention may contain buffering agents, stabilizers, bulking agents, surfactants and/or other excipients. The present invention also provides formulations for lyophilization, reconstitution and methods of use thereof.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
29 November 2011
Publication Number
08/2013
Publication Type
INA
Invention Field
TRADITIONAL KNOWLEDGE BIOTECHNOLOGY
Status
Email
Parent Application

Applicants

WYETH LLC
FIVE GIRALDA FARMS, MADISON, NEW JERSEY, 07940 USA

Inventors

1. KANTOR ANGELA
118 SOUTH ROAD, PEPPERELL, MASSACHUSETTS, 01463 USA.
2. LI LI
32 POKONOKET AVENUE, SUDBURY, MASSACHUSETTS, 01776 USA
3. LUKSHA NICHOLAS
80 DEXTER STREET, MALDEN, MASSACHUSETTS, 02148, USA
4. TECHESSALOV SERGUEI
19 ABBOT BRIDGE DRIVE, ANDOVER, MASSACHUSETTS, 01810, USA
5. WARNE NICHOLAS
27 FARRWOOD DRIVE, ANDOVER, MASSACHUSETTS, 01810, USA

Specification

NA

Documents

Application Documents

# Name Date
1 9374-DELNP-2011-AbandonedLetter.pdf 2017-11-09
1 9374-delnp-2011-Correspondence-Others-(01-02-2012).pdf 2012-02-01
2 9374-DELNP-2011-FER.pdf 2017-03-30
2 9374-delnp-2011-Form-1-(15-02-2012).pdf 2012-02-15
3 SEQUENCE LISTING.pdf 2015-08-18
3 9374-delnp-2011-Correspondence-Others-(15-02-2012).pdf 2012-02-15
4 9374-delnp-2011-GPA.pdf 2012-06-08
4 9374-delnp-2011-Abstract.pdf 2012-06-08
5 9374-delnp-2011-Form-5.pdf 2012-06-08
5 9374-delnp-2011-Claims.pdf 2012-06-08
6 9374-delnp-2011-Form-3.pdf 2012-06-08
6 9374-delnp-2011-Correspondence-others.pdf 2012-06-08
7 9374-delnp-2011-Form-2.pdf 2012-06-08
7 9374-delnp-2011-Description (Complete).pdf 2012-06-08
8 9374-delnp-2011-Drawings.pdf 2012-06-08
8 9374-delnp-2011-Form-18.pdf 2012-06-08
9 9374-delnp-2011-Form-1.pdf 2012-06-08
10 9374-delnp-2011-Form-18.pdf 2012-06-08
10 9374-delnp-2011-Drawings.pdf 2012-06-08
11 9374-delnp-2011-Form-2.pdf 2012-06-08
11 9374-delnp-2011-Description (Complete).pdf 2012-06-08
12 9374-delnp-2011-Form-3.pdf 2012-06-08
12 9374-delnp-2011-Correspondence-others.pdf 2012-06-08
13 9374-delnp-2011-Form-5.pdf 2012-06-08
13 9374-delnp-2011-Claims.pdf 2012-06-08
14 9374-delnp-2011-GPA.pdf 2012-06-08
14 9374-delnp-2011-Abstract.pdf 2012-06-08
15 SEQUENCE LISTING.pdf 2015-08-18
15 9374-delnp-2011-Correspondence-Others-(15-02-2012).pdf 2012-02-15
16 9374-delnp-2011-Form-1-(15-02-2012).pdf 2012-02-15
16 9374-DELNP-2011-FER.pdf 2017-03-30
17 9374-delnp-2011-Correspondence-Others-(01-02-2012).pdf 2012-02-01
17 9374-DELNP-2011-AbandonedLetter.pdf 2017-11-09

Search Strategy

1 searchstrategy_30-03-2017.pdf