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"Method For Controlling Streptococcus Pneumoniae Polysaccharide Molecular Weight Using Carbon"
Abstract: The present invention provides improved methods for producing a solution containing high molecular weight isolated Streptococcus pneumoniae capsular polysaccharides having phosphodiester linkages between saccharide repeat units. In certain methods, CO2 is supplied to a fermentation culture of Streptococcus pneumoniae bacterial cells that produce capsular polysaccharide serotypes containing phosphodiester linkages between saccharide repeat units. Exemplary Streptococcus pneumoniae serotypes containing a phosphodiester linkage between saccharide repeat units include serotypes 6A, 6B, 19A, and 19F. Supplying CO2 to the fermentation culture includes adding bicarbonate ions to the fermentation culture, adding carbonate ions to the fermentation culture, adding mixtures of bicarbonate and carbonate ions to the fermentation culture, and overlaying the fermentation culture with CO2.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
13 May 2011
Publication Number
14/2012
Publication Type
INA
Invention Field
BIOTECHNOLOGY
Status
Email
Parent Application
Patent Number
Legal Status
Grant Date
2018-02-22
Renewal Date
Applicants
WYETH LLC
PATENT LAW DEPARTMENT, FIVE GIRALDA FARMS, MADISON, NEW JERSEY, 07940 U.S.A.
Inventors
1. CRINEAN JEAN HEATHER
3508 GLADE RUN DRIVE, SANFORD, NORTH CAROLINA 27330, U.S.A.
Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 3624-delnp-2011-Correspondence-others-(24-05-2011).pdf | 2011-05-24 |
| 1 | 3624-DELNP-2011-PROOF OF ALTERATION [08-06-2023(online)].pdf | 2023-06-08 |
| 2 | 3624-delnp-2011-Assignment-(24-05-2011).pdf | 2011-05-24 |
| 2 | 3624-DELNP-2011-RELEVANT DOCUMENTS [08-06-2023(online)].pdf | 2023-06-08 |
| 3 | 3624-DELNP-2011-PROOF OF ALTERATION [07-06-2023(online)].pdf | 2023-06-07 |
| 3 | 3624-delnp-2011-Form-3-(29-08-2011).pdf | 2011-08-29 |
| 4 | 3624-DELNP-2011-RELEVANT DOCUMENTS [24-09-2022(online)].pdf | 2022-09-24 |
| 4 | 3624-delnp-2011-Correspondence-Others-(29-08-2011).pdf | 2011-08-29 |
| 5 | 3624-DELNP-2011-RELEVANT DOCUMENTS [07-09-2022(online)].pdf | 2022-09-07 |
| 5 | 3624-delnp-2011-GPA.pdf | 2012-01-19 |
| 6 | 3624-DELNP-2011-RELEVANT DOCUMENTS [02-09-2021(online)].pdf | 2021-09-02 |
| 6 | 3624-delnp-2011-Form-5.pdf | 2012-01-19 |
| 7 | 3624-DELNP-2011-RELEVANT DOCUMENTS [14-02-2020(online)].pdf | 2020-02-14 |
| 7 | 3624-delnp-2011-Form-3.pdf | 2012-01-19 |
| 8 | 3624-DELNP-2011-RELEVANT DOCUMENTS [05-03-2019(online)].pdf | 2019-03-05 |
| 8 | 3624-delnp-2011-Form-2.pdf | 2012-01-19 |
| 9 | 3624-DELNP-2011-Correspondence-190218.pdf | 2018-02-23 |
| 9 | 3624-delnp-2011-Form-18.pdf | 2012-01-19 |
| 10 | 3624-delnp-2011-Form-1.pdf | 2012-01-19 |
| 10 | 3624-DELNP-2011-OTHERS-190218.pdf | 2018-02-23 |
| 11 | 3624-delnp-2011-Drawings.pdf | 2012-01-19 |
| 11 | 3624-DELNP-2011-IntimationOfGrant22-02-2018.pdf | 2018-02-22 |
| 12 | 3624-delnp-2011-Description (Complete).pdf | 2012-01-19 |
| 12 | 3624-DELNP-2011-PatentCertificate22-02-2018.pdf | 2018-02-22 |
| 13 | 3624-delnp-2011-Correspondence Others.pdf | 2012-01-19 |
| 13 | 3624-DELNP-2011-Written submissions and relevant documents (MANDATORY) [13-02-2018(online)].pdf | 2018-02-13 |
| 14 | 3624-delnp-2011-Claims.pdf | 2012-01-19 |
| 14 | 3624-delnp-2011-ExtendedHearingNoticeLetter_16Feb2018.pdf | 2018-01-19 |
| 15 | 3624-delnp-2011-Abstract.pdf | 2012-01-19 |
| 15 | 3624-DELNP-2011-FORM 3 [19-01-2018(online)].pdf | 2018-01-19 |
| 16 | 3624-delnp-2011-Correspondence Others-(24-07-2014).pdf | 2014-07-24 |
| 16 | 3624-DELNP-2011-REQUEST FOR ADJOURNMENT OF HEARING UNDER RULE 129A [18-01-2018(online)].pdf | 2018-01-18 |
| 17 | 3624-delnp-2011-Others-(10-07-2015).pdf | 2015-07-10 |
| 17 | 3624-DELNP-2011-HearingNoticeLetter.pdf | 2018-01-12 |
| 18 | 3624-delnp-2011-Form-3-(10-07-2015).pdf | 2015-07-10 |
| 18 | 3624-DELNP-2011_EXAMREPORT.pdf | 2016-06-30 |
| 19 | 3624-delnp-2011-Correspondence Others-(10-07-2015).pdf | 2015-07-10 |
| 19 | 3624-delnp-2011-Correspondence Others-(28-04-2016).pdf | 2016-04-28 |
| 20 | Claims [19-01-2016(online)].pdf | 2016-01-19 |
| 20 | OTHERS [19-01-2016(online)].pdf | 2016-01-19 |
| 21 | Description(Complete) [19-01-2016(online)].pdf | 2016-01-19 |
| 21 | Examination Report Reply Recieved [19-01-2016(online)].pdf | 2016-01-19 |
| 22 | Description(Complete) [19-01-2016(online)].pdf | 2016-01-19 |
| 22 | Examination Report Reply Recieved [19-01-2016(online)].pdf | 2016-01-19 |
| 23 | Claims [19-01-2016(online)].pdf | 2016-01-19 |
| 23 | OTHERS [19-01-2016(online)].pdf | 2016-01-19 |
| 24 | 3624-delnp-2011-Correspondence Others-(28-04-2016).pdf | 2016-04-28 |
| 24 | 3624-delnp-2011-Correspondence Others-(10-07-2015).pdf | 2015-07-10 |
| 25 | 3624-delnp-2011-Form-3-(10-07-2015).pdf | 2015-07-10 |
| 25 | 3624-DELNP-2011_EXAMREPORT.pdf | 2016-06-30 |
| 26 | 3624-DELNP-2011-HearingNoticeLetter.pdf | 2018-01-12 |
| 26 | 3624-delnp-2011-Others-(10-07-2015).pdf | 2015-07-10 |
| 27 | 3624-delnp-2011-Correspondence Others-(24-07-2014).pdf | 2014-07-24 |
| 27 | 3624-DELNP-2011-REQUEST FOR ADJOURNMENT OF HEARING UNDER RULE 129A [18-01-2018(online)].pdf | 2018-01-18 |
| 28 | 3624-delnp-2011-Abstract.pdf | 2012-01-19 |
| 28 | 3624-DELNP-2011-FORM 3 [19-01-2018(online)].pdf | 2018-01-19 |
| 29 | 3624-delnp-2011-Claims.pdf | 2012-01-19 |
| 29 | 3624-delnp-2011-ExtendedHearingNoticeLetter_16Feb2018.pdf | 2018-01-19 |
| 30 | 3624-delnp-2011-Correspondence Others.pdf | 2012-01-19 |
| 30 | 3624-DELNP-2011-Written submissions and relevant documents (MANDATORY) [13-02-2018(online)].pdf | 2018-02-13 |
| 31 | 3624-delnp-2011-Description (Complete).pdf | 2012-01-19 |
| 31 | 3624-DELNP-2011-PatentCertificate22-02-2018.pdf | 2018-02-22 |
| 32 | 3624-delnp-2011-Drawings.pdf | 2012-01-19 |
| 32 | 3624-DELNP-2011-IntimationOfGrant22-02-2018.pdf | 2018-02-22 |
| 33 | 3624-delnp-2011-Form-1.pdf | 2012-01-19 |
| 33 | 3624-DELNP-2011-OTHERS-190218.pdf | 2018-02-23 |
| 34 | 3624-DELNP-2011-Correspondence-190218.pdf | 2018-02-23 |
| 34 | 3624-delnp-2011-Form-18.pdf | 2012-01-19 |
| 35 | 3624-delnp-2011-Form-2.pdf | 2012-01-19 |
| 35 | 3624-DELNP-2011-RELEVANT DOCUMENTS [05-03-2019(online)].pdf | 2019-03-05 |
| 36 | 3624-DELNP-2011-RELEVANT DOCUMENTS [14-02-2020(online)].pdf | 2020-02-14 |
| 36 | 3624-delnp-2011-Form-3.pdf | 2012-01-19 |
| 37 | 3624-DELNP-2011-RELEVANT DOCUMENTS [02-09-2021(online)].pdf | 2021-09-02 |
| 37 | 3624-delnp-2011-Form-5.pdf | 2012-01-19 |
| 38 | 3624-DELNP-2011-RELEVANT DOCUMENTS [07-09-2022(online)].pdf | 2022-09-07 |
| 38 | 3624-delnp-2011-GPA.pdf | 2012-01-19 |
| 39 | 3624-DELNP-2011-RELEVANT DOCUMENTS [24-09-2022(online)].pdf | 2022-09-24 |
| 39 | 3624-delnp-2011-Correspondence-Others-(29-08-2011).pdf | 2011-08-29 |
| 40 | 3624-DELNP-2011-PROOF OF ALTERATION [07-06-2023(online)].pdf | 2023-06-07 |
| 40 | 3624-delnp-2011-Form-3-(29-08-2011).pdf | 2011-08-29 |
| 41 | 3624-DELNP-2011-RELEVANT DOCUMENTS [08-06-2023(online)].pdf | 2023-06-08 |
| 41 | 3624-delnp-2011-Assignment-(24-05-2011).pdf | 2011-05-24 |
| 42 | 3624-delnp-2011-Correspondence-others-(24-05-2011).pdf | 2011-05-24 |
| 42 | 3624-DELNP-2011-PROOF OF ALTERATION [08-06-2023(online)].pdf | 2023-06-08 |