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Oligonucleotide Compositions And Methods Relating Thereto
Abstract: The present disclosure features useful oligonucleotide compositions and methods related thereto. The present disclosure encompasses the recognition that structural elements of oligonucleotides, such as base sequence, chemical modifications (e.g. modifications of sugar, base and/or internucleotide linkages) or patterns thereof, can have a significant impact on oligonucleotide properties and activities. The present disclosure also provides methods to treat disorders for which deamination of an adenosine in an mRNA produces a therapeutic result, e.g., in a subject in need thereof.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
04 October 2024
Publication Number
51/2024
Publication Type
INA
Invention Field
BIO-CHEMISTRY
Status
Email
Parent Application
Applicants
WAVE LIFE SCIENCES LTD.
7 Straits View #12-00
Marina One East Tower
Singapore 018936
Inventors
1. LU, Genliang
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
2. MONIAN, Prashant
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambrige, Massachusetts 02138
3. SHIVALILA, Chikdu Shakti
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
4. GODFREY, Jack David
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
5. HARDING, Ian Chandler
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
6. GIANGRANDE, Paloma Hoban
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
7. PU, Tom Liantang
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
8. KOTHARI, Nayantara
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
9. MARAPPAN, Subramanian
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
10. VARGEESE, Chandra
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
11. KANDASAMY, Pachamuthu
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
12. YU, Hui
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
13. KUMARASAMY, Jayakanthan
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
14. IWAMOTO, Naoki
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
15. STANDLEY, Stephany Michelle
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
16. SHIMIZU, Mamoru
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
17. RYAN, Timothy Charles
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
18. DESAI, Jigar
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
19. LAMATTINA, Anthony
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
20. SAMARAWEERA, Milinda Amila Kumara
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
21. LIU, Wei
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
22. SCHRAND, Brett
c/o WAVE LIFE SCIENCES LTD.
733 Concord Avenue
Cambridge, Massachusetts 02138
Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 202417075332-STATEMENT OF UNDERTAKING (FORM 3) [04-10-2024(online)].pdf | 2024-10-04 |
| 2 | 202417075332-REQUEST FOR EXAMINATION (FORM-18) [04-10-2024(online)].pdf | 2024-10-04 |
| 3 | 202417075332-POWER OF AUTHORITY [04-10-2024(online)].pdf | 2024-10-04 |
| 4 | 202417075332-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [04-10-2024(online)].pdf | 2024-10-04 |
| 5 | 202417075332-FORM 18 [04-10-2024(online)].pdf | 2024-10-04 |
| 6 | 202417075332-FORM 1 [04-10-2024(online)].pdf | 2024-10-04 |
| 7 | 202417075332-DRAWINGS [04-10-2024(online)].pdf | 2024-10-04 |
| 8 | 202417075332-DECLARATION OF INVENTORSHIP (FORM 5) [04-10-2024(online)].pdf | 2024-10-04 |
| 9 | 202417075332-COMPLETE SPECIFICATION [04-10-2024(online)].pdf | 2024-10-04 |
| 10 | 202417075332-Proof of Right [29-11-2024(online)].pdf | 2024-11-29 |
| 11 | 202417075332-FORM 3 [01-04-2025(online)].pdf | 2025-04-01 |