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Pyridazinyl Phenyl Hydrazone Compounds And Pharmaceutical Composition Containing The Same
Therapeutically active compounds of formula (I) in which R1 to R4 means hydrogen, alkyl, alkenyl, aryl, arylalkyl, carboxyalkyl, hydroxyalkyl or halogenalkyl, or R2 and R3 form a ring of 5-7 carbon atoms, R5 to R9 means hydrogen, alkyl, alkenyl, aryl, arylalkyl, acyl, hydroxy, alkoxy, alkoxycarbonyl, amino, acylamino, alkylamino, aryloxy, halogen, cyano, nitro, carboxy, alkylsulfonyl, sulfonamido or trifluoromethyl, wherein each aryl residue defined above by itself or as a part of another group may be substituted, and pharmaceutically acceptable salts and esters thereof. The compounds increase the calcium sensitivity of contractile proteins of the cardiac muscle and are thus useful in the treatment of congestive heart failure.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
02 September 2002
Publication Number
08/2005
Publication Type
Invention Field
CHEMICAL
Status
Email
Parent Application
Patent Number
Legal Status
Grant Date
2008-08-13
Renewal Date
Applicants
ORION CORPORATION
ORIONINTIE 1, FIN-02200 ESPOO,
Inventors
1. PYSTYNEN JARMO
II VISNIEMENTIE 6 A 5, FIN 02260 ESPOO,
2. PIPPURI AINO
KAITAANPORTTI 4A, FIN 02360 ESPOO
3. LUIRO ANNE
SIILITIE 6 C 14, FIN 00800 HELSINKI
4. NORE PENTII
MALMINKATU 24 E 52, FIN 00100 HELSINKI
5. BACKSTROM REIJO
POUTAMAENTIE 14 F 68, FIN 00360 HELSINKI
6. LONNBERG KARI
MALMINMAENTIE 5 A 1, FIN 02280 ESPOO,
7. HAIKALA HEIMO
SEILIMAKI 18 A 4, FIN 02180 ESPOO
8. LEVIJOKI JOUKO
AIRPTIE 5 A, FIN 00830 HELSINKI
9. KAHEINEN PETRI
TOPELIUKSENKATU 7 B 24, FIN 00250 HELSINKI,
10. KAIVOLA JUHA
PTAVANTIE 4 A 11, FIN 00200 HELSINKI,
Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | in-pct-2002-1121-kol-granted-translated copy of priority document.pdf | 2011-10-08 |
| 2 | in-pct-2002-1121-kol-granted-specification.pdf | 2011-10-08 |
| 3 | in-pct-2002-1121-kol-granted-reply to examination report.pdf | 2011-10-08 |
| 4 | in-pct-2002-1121-kol-granted-letter patent.pdf | 2011-10-08 |
| 5 | in-pct-2002-1121-kol-granted-gpa.pdf | 2011-10-08 |
| 6 | in-pct-2002-1121-kol-granted-form 5.pdf | 2011-10-08 |
| 7 | in-pct-2002-1121-kol-granted-form 3.pdf | 2011-10-08 |
| 8 | in-pct-2002-1121-kol-granted-form 18.pdf | 2011-10-08 |
| 9 | in-pct-2002-1121-kol-granted-form 1.pdf | 2011-10-08 |
| 10 | in-pct-2002-1121-kol-granted-examination report.pdf | 2011-10-08 |
| 11 | in-pct-2002-1121-kol-granted-description (complete).pdf | 2011-10-08 |
| 12 | in-pct-2002-1121-kol-granted-correspondence.pdf | 2011-10-08 |
| 13 | in-pct-2002-1121-kol-granted-claims.pdf | 2011-10-08 |
| 14 | in-pct-2002-1121-kol-granted-assignment.pdf | 2011-10-08 |
| 15 | in-pct-2002-1121-kol-granted-abstract.pdf | 2011-10-08 |
| 16 | IN-PCT-2002-1121-KOL-FORM 27.pdf | 2011-10-08 |
| 17 | IN-PCT-2002-1121-KOL-CORRESPONDENCE.pdf | 2011-10-08 |
| 18 | IN-PCT-2002-1121-KOL-27-01-2023-ALL DOCUMENTS.pdf | 2023-01-27 |
| 19 | IN-PCT-2002-1121-KOL-22-02-2023-RELEVANT DOCUMENTS.pdf | 2023-02-22 |