Abstract: The present invention relates to a stable non-aqueous, ready to dilute liquid pharmaceutical composition comprising (i) melphalan or a pharmaceutically acceptable salt thereof and (ii) polyoxyethylene sorbitan fatty acid esters; wherein the weight ratio of melphalan to polyoxyethylene sorbitan fatty acid esters is from about 1:0.75 to about 1:20; wherein, composition comprising melphalan, at a concentration of about 50 mg/ml to about 150 mg/ml; wherein, when the composition is diluted to produce melphalan at a concentration of about 0.1 to about 3 mg/ml, is physically and chemically stable up to about 4 hours.
| # | Name | Date |
|---|---|---|
| 1 | 202047032912.pdf | 2020-07-31 |
| 2 | 202047032912-STATEMENT OF UNDERTAKING (FORM 3) [31-07-2020(online)].pdf | 2020-07-31 |
| 3 | 202047032912-REQUEST FOR EXAMINATION (FORM-18) [31-07-2020(online)].pdf | 2020-07-31 |
| 4 | 202047032912-FORM 18 [31-07-2020(online)].pdf | 2020-07-31 |
| 5 | 202047032912-FORM 1 [31-07-2020(online)].pdf | 2020-07-31 |
| 6 | 202047032912-DECLARATION OF INVENTORSHIP (FORM 5) [31-07-2020(online)].pdf | 2020-07-31 |
| 7 | 202047032912-COMPLETE SPECIFICATION [31-07-2020(online)].pdf | 2020-07-31 |
| 8 | 202047032912-OTHERS [16-06-2021(online)].pdf | 2021-06-16 |
| 9 | 202047032912-FER_SER_REPLY [16-06-2021(online)].pdf | 2021-06-16 |
| 10 | 202047032912-FER_SER_REPLY [16-06-2021(online)]-1.pdf | 2021-06-16 |
| 11 | 202047032912-CORRESPONDENCE [16-06-2021(online)].pdf | 2021-06-16 |
| 12 | 202047032912-CORRESPONDENCE [16-06-2021(online)]-1.pdf | 2021-06-16 |
| 13 | 202047032912-COMPLETE SPECIFICATION [16-06-2021(online)].pdf | 2021-06-16 |
| 14 | 202047032912-CLAIMS [16-06-2021(online)].pdf | 2021-06-16 |
| 15 | 202047032912-CLAIMS [16-06-2021(online)]-1.pdf | 2021-06-16 |
| 16 | 202047032912-ABSTRACT [16-06-2021(online)].pdf | 2021-06-16 |
| 17 | 202047032912-FER.pdf | 2021-10-18 |
| 18 | 202047032912-US(14)-HearingNotice-(HearingDate-23-11-2021).pdf | 2021-10-20 |
| 19 | 202047032912-PETITION UNDER RULE 137 [03-12-2021(online)].pdf | 2021-12-03 |
| 20 | 202047032912-Written submissions and relevant documents [07-12-2021(online)].pdf | 2021-12-07 |
| 21 | 202047032912-Annexure [07-12-2021(online)].pdf | 2021-12-07 |
| 22 | 202047032912-PatentCertificate09-09-2022.pdf | 2022-09-09 |
| 23 | 202047032912-IntimationOfGrant09-09-2022.pdf | 2022-09-09 |
| 24 | 202047032912-Form 4 [06-06-2024(online)].pdf | 2024-06-06 |
| 25 | 202047032912-FORM 4 [12-06-2024(online)].pdf | 2024-06-12 |
| 1 | SearchE_11-11-2020.pdf |