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Stable Liquid Compositions Of Melphalan
Abstract: The present invention relates to a stable non-aqueous, ready to dilute liquid pharmaceutical composition comprising (i) melphalan or a pharmaceutically acceptable salt thereof and (ii) polyoxyethylene sorbitan fatty acid esters; wherein the weight ratio of melphalan to polyoxyethylene sorbitan fatty acid esters is from about 1:0.75 to about 1:20; wherein, composition comprising melphalan, at a concentration of about 50 mg/ml to about 150 mg/ml; wherein, when the composition is diluted to produce melphalan at a concentration of about 0.1 to about 3 mg/ml, is physically and chemically stable up to about 4 hours.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
31 July 2020
Publication Number
40/2020
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
chandramohan.sb@orbicular.co.in
Parent Application
Patent Number
Legal Status
Grant Date
2022-09-09
Renewal Date
Applicants
ORBICULAR PHARMACEUTICAL TECHNOLOGIES PRIVATE LIMITED
P. No. 53, Aleap Industrial Estate,
Pragati Nagar,
Kukatpally, Hyderabad 500090, Telangana
Inventors
1. PATEL, Hiren
Orbicular Pharmaceutical Technologies PVT. LTD.
P. No. 53
Aleap Industrial Estate
Pragati Nagar,
Kukatpally, Telangana
Hyderabad 500090
2. PATEL, Bhaveshkumar Vallabhbhai
Orbicular Pharmaceutical Technologies PVT. LTD.
P. No. 53
Aleap Industrial Estate
Pragati Nagar,
Kukatpally, Telangana
Hyderabad 500090
3. KANNEKANTI, Raghu
Orbicular Pharmaceutical Technologies PVT. LTD.
P. No. 53
Aleap Industrial Estate
Pragati Nagar,
Kukatpally, Telangana
Hyderabad 500090
4. KANTU, Babuji
Orbicular Pharmaceutical Technologies PVT. LTD.
P. No. 53
Aleap Industrial Estate
Pragati Nagar,
Kukatpally, Telangana
Hyderabad 500090
5. SANKA, Mahesh
Orbicular Pharmaceutical Technologies PVT. LTD.
P. No. 53
Aleap Industrial Estate
Pragati Nagar,
Kukatpally, Telangana
Hyderabad 500090
Specification
Documents
Orders
| Section | Controller | Decision Date |
|---|---|---|
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 202047032912-FORM 4 [12-06-2024(online)].pdf | 2024-06-12 |
| 1 | 202047032912.pdf | 2020-07-31 |
| 2 | 202047032912-Form 4 [06-06-2024(online)].pdf | 2024-06-06 |
| 2 | 202047032912-STATEMENT OF UNDERTAKING (FORM 3) [31-07-2020(online)].pdf | 2020-07-31 |
| 3 | 202047032912-REQUEST FOR EXAMINATION (FORM-18) [31-07-2020(online)].pdf | 2020-07-31 |
| 3 | 202047032912-IntimationOfGrant09-09-2022.pdf | 2022-09-09 |
| 4 | 202047032912-PatentCertificate09-09-2022.pdf | 2022-09-09 |
| 4 | 202047032912-FORM 18 [31-07-2020(online)].pdf | 2020-07-31 |
| 5 | 202047032912-FORM 1 [31-07-2020(online)].pdf | 2020-07-31 |
| 5 | 202047032912-Annexure [07-12-2021(online)].pdf | 2021-12-07 |
| 6 | 202047032912-Written submissions and relevant documents [07-12-2021(online)].pdf | 2021-12-07 |
| 6 | 202047032912-DECLARATION OF INVENTORSHIP (FORM 5) [31-07-2020(online)].pdf | 2020-07-31 |
| 7 | 202047032912-PETITION UNDER RULE 137 [03-12-2021(online)].pdf | 2021-12-03 |
| 7 | 202047032912-COMPLETE SPECIFICATION [31-07-2020(online)].pdf | 2020-07-31 |
| 8 | 202047032912-US(14)-HearingNotice-(HearingDate-23-11-2021).pdf | 2021-10-20 |
| 8 | 202047032912-OTHERS [16-06-2021(online)].pdf | 2021-06-16 |
| 9 | 202047032912-FER.pdf | 2021-10-18 |
| 9 | 202047032912-FER_SER_REPLY [16-06-2021(online)].pdf | 2021-06-16 |
| 10 | 202047032912-ABSTRACT [16-06-2021(online)].pdf | 2021-06-16 |
| 10 | 202047032912-FER_SER_REPLY [16-06-2021(online)]-1.pdf | 2021-06-16 |
| 11 | 202047032912-CLAIMS [16-06-2021(online)]-1.pdf | 2021-06-16 |
| 11 | 202047032912-CORRESPONDENCE [16-06-2021(online)].pdf | 2021-06-16 |
| 12 | 202047032912-CLAIMS [16-06-2021(online)].pdf | 2021-06-16 |
| 12 | 202047032912-CORRESPONDENCE [16-06-2021(online)]-1.pdf | 2021-06-16 |
| 13 | 202047032912-COMPLETE SPECIFICATION [16-06-2021(online)].pdf | 2021-06-16 |
| 14 | 202047032912-CLAIMS [16-06-2021(online)].pdf | 2021-06-16 |
| 14 | 202047032912-CORRESPONDENCE [16-06-2021(online)]-1.pdf | 2021-06-16 |
| 15 | 202047032912-CLAIMS [16-06-2021(online)]-1.pdf | 2021-06-16 |
| 15 | 202047032912-CORRESPONDENCE [16-06-2021(online)].pdf | 2021-06-16 |
| 16 | 202047032912-ABSTRACT [16-06-2021(online)].pdf | 2021-06-16 |
| 16 | 202047032912-FER_SER_REPLY [16-06-2021(online)]-1.pdf | 2021-06-16 |
| 17 | 202047032912-FER_SER_REPLY [16-06-2021(online)].pdf | 2021-06-16 |
| 17 | 202047032912-FER.pdf | 2021-10-18 |
| 18 | 202047032912-OTHERS [16-06-2021(online)].pdf | 2021-06-16 |
| 18 | 202047032912-US(14)-HearingNotice-(HearingDate-23-11-2021).pdf | 2021-10-20 |
| 19 | 202047032912-PETITION UNDER RULE 137 [03-12-2021(online)].pdf | 2021-12-03 |
| 19 | 202047032912-COMPLETE SPECIFICATION [31-07-2020(online)].pdf | 2020-07-31 |
| 20 | 202047032912-Written submissions and relevant documents [07-12-2021(online)].pdf | 2021-12-07 |
| 20 | 202047032912-DECLARATION OF INVENTORSHIP (FORM 5) [31-07-2020(online)].pdf | 2020-07-31 |
| 21 | 202047032912-FORM 1 [31-07-2020(online)].pdf | 2020-07-31 |
| 21 | 202047032912-Annexure [07-12-2021(online)].pdf | 2021-12-07 |
| 22 | 202047032912-PatentCertificate09-09-2022.pdf | 2022-09-09 |
| 22 | 202047032912-FORM 18 [31-07-2020(online)].pdf | 2020-07-31 |
| 23 | 202047032912-REQUEST FOR EXAMINATION (FORM-18) [31-07-2020(online)].pdf | 2020-07-31 |
| 23 | 202047032912-IntimationOfGrant09-09-2022.pdf | 2022-09-09 |
| 24 | 202047032912-STATEMENT OF UNDERTAKING (FORM 3) [31-07-2020(online)].pdf | 2020-07-31 |
| 24 | 202047032912-Form 4 [06-06-2024(online)].pdf | 2024-06-06 |
| 25 | 202047032912-FORM 4 [12-06-2024(online)].pdf | 2024-06-12 |
| 25 | 202047032912.pdf | 2020-07-31 |
Search Strategy
| 1 | SearchE_11-11-2020.pdf |