A sweetener composition is described which augments full benefit of reduced calorific value associated through use of high intensity sweeteners as dominant sweetness contributors, and yet avoids problem of loss of favorable organoleptic properties associated with their use by incorporating sugars and other non-sugar...

A process is described for extraction of 6- acyl - 4,1’, 6’ trichlorogalactosucrose abbreviated as TGS-6-ester from a process stream containing one or more of TGS-6-ester and impurities including DMF, requiring DMF removal, comprising neutralization of the process stream, adjustment of pH thereafter to acidic side, ...

A process of azeotropic removal of dimethylformamide, abbreviated as DMF, from a process stream containing DMF requiring its removal, is described wherein the said Process Stream being .obtained in a process for preparation of 4,1 ', 6' trichlorogalactosucrose, abbreviated as TGS, or TGS-6-ester including TGS-6-acet...

A process of removal of pyridine or a pyridine analogue from a composition or a Process Stream in a process of production of 4,1’, 6’ trichlorogalactosucrose is described comprising reacting pyridine with an acid, the said acid being used preferably in gaseous form, achieving complete precipitation of the salt of py...

A process is described for acid mediated deacylation of acyl derivatives of chlorinated sucrose compounds comprising generating a predominantly organic phase condition in a process stream requiring deacylation treatment but allowing an optimum quantity of water content which is capable of participating in a hydrolys...

A process is described for production of a chlorinated sucrose from a process stream containing a 6-O-protected chlorinated sucrose derived from chlorination of 6-O-protected sucrose wherein the process stream is treated under conditions which prevent or reverse deacylation of 6-O-protected chlorinated sucrose, extr...

A process is described which uses whole cell preparations, immobilized or without immobilization, of a microorganism, including Aureobasidium pullulans, capable of forming enzymes of the group of fructosyltransferases, for catalyzing a reaction between sucrose and 6-0-protected glucose for formation of 6-0-protected...

An improved process of production of a chlorinated sugar is described comprising chlorination of a partially protected sugar, wherein quenching as well as neutralization of chlorinated reaction mass is carried out concurrently and continuously in a reactor which is a continuous mixer as well as quencher providing co...

This invention comprises an improved process for recovery and purification of DMF from an aqueous process stream containing DMF with or without inorganic impurities, particularly from process stream of a process of manufacture of the high intensity sweetener Trichlorogalactosurose, by adsorption on an adsorbent havi...

A process of production of 1'-6'-Dichloro-1'-6'-DIDEOXY-p-Fructofuranasyl-4-chloro-4-deoxy-galactopyranoside abbreviated as TGS, or 6- acyl - 4,1', 6' trichlorogalactosucrose abbreviated as TGS-6-ester comprising a process stream containing one or more of TGS-6-ester, DMF, one or more of an inorganic salt, one or mo...

A process of azeotropic removal of dimethylformamide, abbreviated as DMF, from a process stream containing DMF requiring its removal, is described wherein the said process stream being obtained in a process for preparation pf 4,1’,6’ trichlorogalactosucrose, abbreviated as TGS, or TGS-6-ester including TGS-6acetate ...

An improved process for chlorination is described wherein a solution of chlorinating agent and solution of sucrose-6-ester are mixed together by co-addition to a reaction vessel, the addition of both the reactants starting and completing substantially at the same time. The product of chlorinated sucrose is further e...

This invention relates to a process for selective capture isolation and purification of chlorinated sucrose compounds, including chlorinated sucrose, their precursors and derivatives, including trichlorogalactosucrose (TGS), directly from chlorinated reaction mixture by column chromatography on adsorbents and under ...

A process is described for enzymatic removal of an ester group to transform a sucrose-6,6"-diester to a sucrose-6-ester. The sucrose-6-ester formed in this way can be subjected to a process of production of trichlorogalactosucrose comprising steps of chlorination, neutralization, deacylation, isolation and purificat...

A process is described for acid mediated deacylation of acyl derivatives of chlorinated sucrose compounds comprising generating a predominantly organic phase condition in a process stream requiring deacylation treatment but allowing an optimum quantity of water content which is capable of participating in a hydrolys...

Present invention relates to disclosure of application of some innovative techniques useful for substantially improving process efficiency of production of chlorinated sucrose including their intermediates and derivatives. Application of mild methods of drying has been made for recovery of chlorinated sucrose or the...

A process of preparation of Vilsmeier-Haack reagent is provided where di (trichloromethyl) carbonate reacts with N,N-dimethylformamide to form a Vilsmeier reagent, which can be used efficiently for chlorination of sucrose-6-acetate or sucrose-6-benzoate and other sucrose acylates. This process has application in the...

A process is described wherein after formation of first crop of Vilsmeier-Haack reagent by reacting Phosphorus Pentachloride with N,N-dimethylformamide to form a first crop of Vilsmeier reagent as insoluble crystals, a by-product of this reaction, the Phosphorus Oxy-Chloride, reacts with N,N-dimethylformamide to giv...

A process is described for extractive isolation and purification of Trichlorogalactosucrose from impurities from a composition substantially free from N-N Dimethylformamide (DMF) comprising a first extractive separation by adjusting aqueous to a mixture of organic solvents in the composition to a certain ratio of aq...

A chromatographic process of DMF removal from an aqueous composition is described comprising its loading on a column of hydrophobic fixed bed adsorbent and eluting out DMF with an aqueous alkaline buffer. This method is useful to remove DMF as a process of general application wherever simultaneous removal and isolat...

A process is described in which decolorization of solutions or reaction mixtures containing trichlorogalactosucrose or 6-acetyl trichlorogalactosucrose is achieved described by bubbling ozone. The method can be used at various stages in the process of production and with or without a combination with other adsorbent...

This invention relates to a process for selective capture, isolation and purification of chlorinated sucrose compounds, including chlorinated sucrose, their precursors and derivatives, including trichlorogalactosucrose (TGS), directly from chlorinated reaction mixture by column chromatography on adsorbents and under...

Dislcosed is crystalline 4, 1’,6’ Trichlorogalactosucrose (TGS) having enhanced storage stability, a mean particle size of about 5 microns or less, 90% particles being less than about 10 microns and the maximum particle size being more than twice the mean but less than about 35 microns; and a process for producing t...

A process of production of trichlorogalactosucrose is described in which deacylation of sucrose-6-ester is achieved by subjecting the reaction mixture after chlorination, neutralization and adjustment of pH to 6.5 to 7 to deacylation by using a lipase or a protease, in a free or in an immobilized form. ...

A process of production of trichlorogalactosucrose is described in which deacylation of sucrose-6-ester is achieved by subjecting the reaction mixture after chlorination, neutralization and adjustment of pH to 6.5 to 7 to deacylation by using a lipase or a protease, in a free or in an immobilized form. ...

A process is described to increase efficiency of extraction of 4,1', 6' trichlorogalactosucrose (TGS) from aqueous solution by addition of salt. The invention helps in reducing the quantity of solvent needed for achieving substantial extraction. The invention also leads to extraction of TGS substantially free from p...

A process is described comprising one or more of a step of separation, isolation, purification, concentration, hydrolysis of one or more of a lipid in general or its/their derivative, from a process stream; wherein the said lipid comprises any fat soluble natural molecule and the said process comprising selective ca...

A process of removal of pyridine of a pyridine analogue from a composition from a composition or a process stream in a process pf production of4, 1', 6' trichlorogalactosucrose is described comprising reacting pyridine with an acid, the said acid being used preferably in gaseous from, achieving complete precipitatio...

A process is described which uses whole cell preparations, immobilized or without immobilization, of a microorganism, including Aureobasidium pullulans, capable of forming enzymes of the group of fructosyltransferases, for catalyzing a reaction between sucrose and6-O-protected glucose for formation of 6-O-protected ...

The present invention is directed to new "substituted cyclopropane" intermediate and a method for stereoselective bioconversion to the "S" isomer of y-amino acids.

This invention comprises novel application of a molecular separation process, including one or more of a membrane separation/ filtration process comprising reverse osmosis, micro filtration, nanofiltration ultrafiltration and perevaporation and the like to several process streams obtained in process of production of...

A method is disclosed for regioselective synthesis of sucrose-6-acetate via formation of a novel sucrose-tin adduct using sucrose and DBTO. The novel tin adduct can be represented by a formula (6-O-sucrose) - O -Snbutyl.sub.2 -O- (6-O-sucrose) or as 1,3.( di O-sucrose) dibutyl stannylene. The adduct is acylated to y...

A process is described wherein efficiency of chlorination is improved in a process for production of a chlorinated sucrose by scavenging, using an acid scavenger, of excess of acidic protons formed during a chlorination reaction between 6-0-acyl sucrose in dimethylformamide and a chlorinating reagent. ...

Perparation of chlorinating reagent or chlorination reaction itself for use in a reaction such as production of high intensity sweetener trichlorogalactosucrose (TGS) from partially protected sucrose, comprising reaction of dimethylformamide (DMF) with thionyl chloride or another sulphur containing inorganic acid ch...