The present invention relates to preparation and characterization of HAART combination 655 anti-retroviral drugs loaded lactoferrin nanoparticles for first line and second line therapy. The first line drug combination is Zidovudine (AZT), Efavirenz (EFV) and Lamivudine (LMV) and the second line drug combination i...

BIOPESTICIDE COMPOSITIONS COMPRISING STABLE HARPINPss-LOADED CHITOSAN NANOPARTICLES AND METHODS THEREOF Exemplary embodiments of the present disclosure are directed towards biopesticide compositions for plants comprising stable harpin-loaded chitosan nanoparticles. The composition is a sustained release compositi...

A compound has the of Formula I or a salt thereof:- ( fig I ). Such compounds may be used to image cells, tissues, organs, fluids, or a subject. Such compounds may also be used in pharmaceutical compositions.

An open reading frame (Orf243) which is known to express within the genomic island of spingobium fuliginis ATCC27551 when expressed in E coli allowed it to grow on p-. nitrophenol. Expression of Orf243 in E. coli has been shown to induce a novel sRNA, seco10054A. It has been now shown that the sRNA, SecolOO inhib...

Title: Novel nanoparticles of lactoferrin useful for preparing a pharmaceutical composition facilitating easy delivery of the drug and a process for preparing the same. Novel nanoparticles of lactoferrin useful for preparing a pharmaceutical composition facilitating easy delivery of the drug contained therein wh...

The present invention relates to a polymeric film embedded with silver nano particles and a method for preparing the same, wherein the silver nano-particles grown in situ. More particularly, the said films are useful in applications where antibacterial find utility, such as purification of driking water. The said...

A process for synthesizing higher chain chitooligosaccharides (CHOS) comprising: amplifying chitinase D from S. proteamaculans; subjecting the amplified chitinase D to the step of cloning; purifying the cloned chitinase D analyzing products of Sp chiD from chitooligosaccharides (CHOS). Fig. 1 ...

ABSTRACT “LASER BASED METHOD TO CRYSTALLIZE FERROELECTRIC THIN FILM AT 300ºC TEMPERATURES FOR TUNABLE MICROWAVE DEVICES” The present invention relates to crystallization of ferroelectric thin films. More particularly, the present invention relates to a laser-based method for crystallization of ferroelectric thin...

A novel anti-HIV-1 heteroaromatic compounds targeted to HIV-1 associated topoisomerase II beta kinase is disclosed. A structural study of Dicoumarols with potential activity against a novel HIV-1associated Topoisomerase II ß Kinase target (72 kDa), identified in the HIV-1 viral lysate and anti-HIV-1 activity. The di...

A method and composition for providing the formulation of Efavirenz or Tenofovir or Dapivirine and Curcumin loaded Lactoferrin Nano-particles (ECNPs) to treat Sexually Transmitted Infections (STI’s), and STI-mediated inflammation, contraception in vagina is disclosed. The method includes the step of formulating nano...

The present invention relates to staining and imaging of biological tissue by diaminodicyanoquinodimethane derivatives, particularly 7,7-bis(piperazinium)-8,8-dicyanoquinodimethane bis(p-toluene sulfonate). The derivatives can be used to selective stain guard cells in plant tissue, which is low cost, non-toxic and c...

AS FLUORESCENCE PROBES rhe present invention provides compounds of formula (I) and formula (II): or a pharmaceutical^ acceptable salt or a stereoisomer thereof; wherein, ring A and ring B have the meanings given in the specification. The compounds of the present disclosure are useful as fluorescence probe in detec...

ABSTRACT Novel therapeutic uses of Kisspeptins in reversing aging related neurodegenerative disorders The current invention relates to the field of aging related degenerative changes in the brain, and the method of inducing autophagy and/or mitophagy in neuronal cells by peptides called Kisspeptins. The current in...

The present invention relates to derivatives of Nordihydroguaiaretic acid (NDGA), especially heterocyclic derivatives of NDGA of compound of formula (I) where R is as described herein in the description. The present invention also relates to the pharmaceutically acceptable salts and solvates of these compounds. In a...

ABSTRACT Methods and Compositions for increasing antibiotic uptake in pathogenic bacteria by using NSAID co-crystals The current invention relates to methods and compositions for enhancing the efficacy of antibiotics and for overcoming antibiotic resistance in pathogenic bacteria. The invention specifically rela...

The present invention provides chitosan based multifunctional liquid biofertilizer comprising carboxymethylcellulose, polyvinylpyrrolidone, glycerol, chitosan and at least one plant-growth promoting rhizobacteria selected from Bacillus sp. RS4T, Labrys endophyticus RP1T and combinations thereof. The invention repres...

The present invention provides compounds of formula (I): or a pharmaceutically acceptable salt or a stereoisomer thereof; wherein, R1, R2, R3, R4, R5, R6, m and n have the meanings given in the specification. The compounds of the present disclosure are useful for staining cells particularly as green fluorescent mi...

The present disclosure in general relates to Fog computing, and more particularly to system and methods for dynamic deployment of Fog computations in Internet of Things (IoT) environments. dynamic fog service deployment framework, herein referred to as FogDEFT, comprising: A dynamic fog service deployment frame...

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A novel formulation containing native or recombinant apotranferrin or lactoferrin or transferring nanoparticle loaded with biological molecules alone or in combination with chemotherapeutic agent for targeted delivery is disclosed. The Biological molecules is protected with appropriate materials that permit its stab...

A novel spore selective fluorescent dye, which specifically binds to bacterial spores (both endo and exospores) and a quick and simple technique for fluorescent staining of the spores is provided. The novel stain comprises a specific DADQ derivative, 7,7-bis(n-hexylamino)-8,8-dicyanoquinodimethane (BHADQ) in DMSO so...

The current invention relates to a novel method for separating and purifying Bowman-Birk and Kunitz Inhibitors from plants. These are economically and industrially significant proteinase inhibitor plant proteins that are difficult to separate from each other and also to purify from plant extracts. The current method...

ABSTRACT: Title: NS2BNS3pro Antigen for Diagnosis of Dengue Virus Infections The present disclosure proposes a method that uses a purified dengue virus NS2BNS3pro as an antigen in an indirect diagnostic test for dengue. The proposed method uses purified dengue virus NS2BNS3pro as an antigen in an indirect diagnost...

The present invention describes a novel, cost-effective, and scalable method for synthesizing aluminium encapsulated hollow polymer nanocapsules with a ferrocenyl shell (Al-HPNs) as represented by formula IV. The invention also encompasses the synthetic procedures for producing ferrocenyl polymers, crosslinked polym...

7. ABSTRACT The present invention discloses a method for the preparation of ceramic components featuring a-alumina platelets aimed at enhancing mechanical properties. The process entails synthesizing a-alumina platelets via a sequential procedure involving dissolution, foaming, milling, and calcination. These plate...

ABSTRACT The present invention discloses a method for fabricating components with intricate geometries utilizing Expanded Polystyrene (EPS) molds and slurry-casting techniques. Designing a mold geometry (102) tailored to the desired component shape. The molds are then fabricated from EPS (104) using rapid prototypi...

ABSTRACT This invention discloses nitroaldolase activity of BmHNL, and its application in enantioselective and diastereoselective nitroaldol reaction. Further, the invention relates to broad substrate selectivity of BmHNL in enantioselective and diastereoselective nitroaldol synthesis. It also reveals the catalytic...

5. The current invention relates to two improved hydroxynitrile lyase by substituting different amino acids in the amino acid sequence of a wild-type enzyme, which can catalyze the diastereoselective synthesis of ꞵ-nitroalcohols via the Henry reaction. This new improved hydroxynitrile lyase could carry out the prom...

7. The current invention is relates to improved hydroxynitrile lyases by substituting different amino acids in the amino acid sequence of a wild-type (R)-Hydroxynitrile lyase, which can catalyze the synthesis of optically active ꞵ-nitroalcohols. The use of the mutated enzymes as catalysts in the stereoselective C-C...

7. ABSTRACT The present invention relates to an anti-HIV recombinant HIV-1 derived Topoisomerase IIß kinase. It inhibits HIV-1 replication by blocking viral entry. Its recognition by envelope antibodies ID6 and 4G10 makes it a justifiable immunogen for use as vaccine candidate in form of protein, mRNA and DNA vacc...

7. ABSTRACT A nanoparticle formulation of composed of chemotherapeutic agent or/and biological loaded in alpha lactalbumin nanoparticles. DNA Loaded alpha lactalbumin nanoparticles are characterized using DLS and FE-SEM and an average size of 537nm and 55 nm nanoparticles are produced respectively. In-vitro localiz...

The invention relates to a method for synthesizing a piperidine-based tetraamine monomer, named as PIP-TAB, and its polymerization with various dicarboxic acid monomers such as OBA, BP-COOH, and TP-COOH to develop an advanced, strong, flexible, and transparent polybenzimidazole (PBI)-based membrane. The method to o...

ABSTRACT The present invention relates to a broadband ultralow reflective stainless-steel sheet, wherein complex hierarchical micro–nanostructured surfaces are fabricated by the use of an ultrafast laser on a thin SS sheet (203) by creating a grid of 3D pyramid structures which contain nanodots, flowers, and micro-...

ABSTRACT The present invention relates to a method for producing a composite superconductor material. The method involves synthesizing Bi-2223 precursor powder and Ca0.86Sr0.14CuO2 (I-phase) particles, mixing them in various concentrations, dispersion in a premix, tumbling, polymerization, molding, sintering twice ...

The present invention provides a method of producing poly 3-hydroxybutyrate in high yield and high purity by culturing a strain of Rhodobacter alkalitolerans. The PHB produced is biodegradable and has diverse applications including in food packaging, biomedical articles, drug delivery and use for substitution of con...