Method And System For Probabilistic Typing Of Microbial Strains

Abstract: The invention relates to a microbiological typing method, which comprises providing a database of genetic profiles of microbial strains, a phylogenetic tree, assignments of the genetic profiles to positions in the phylogenetic tree, and frequencies of variation of the profiles in the tree. The typing of a microorganism comprises measuring the genetic profile of the microorganism, determining probabilities of variation of the genetic profiles belonging to the groups with respect to the measured genetic profile, the probabilities of variation being calculated as a function of the frequencies of variation at a predefined level of the phylogenetic tree and of the belonging of the microorganism to one of the microbial groups if an identification performance criterion is reached for the group, the criterion being reached if at least one probability of variation for the group is greater than a first predefined threshold.

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