The present invention relates to a method for detecting at least one microorganism that may be present in a sample, comprising the steps of: a) bringing into contact, in a container: a culture medium that enables the growth and/or detection of microorganisms, said sample and a sensitized solid support; b) subjecting t...

The present invention relates to a method for the in vitro diagnosing of a benign pathology of the prostate or of an adenocarcinoma of the prostate, characterized in that it comprises the step consisting of detection, in a biological sample from a patient suspected of suffering from a benign pathology of the prostat...

The present invention relates in general terms to the field of analysis for example biological analysis. Specifically the present invention relates to an article (10) in particular for biological analysis said article including: a first sheet (12); a second sheet (14) vertically adjacent to said first sheet (12) said ...

The invention relates to a device for preparing and/or treating a biological sample including an assembly (2) of storage chambers (3) and/or reaction chambers intended for receiving a fluid and means arranged to move an amount of fluid from and/or to at least one of the chambers (3) of the assembly (2) of chambers (...

The invention relates to a method for isolating at least one microorganism from a sample likely to be contaminated by said microorganism including the following steps: (a) providing a device for isolating microorganisms including a bottom waterproof layer a nutritional layer which is placed on the bottom layer and w...

The invention relates to a reaction medium for gram-negative bacteria having a beta-lactam antibiotic resistance mechanism, comprising: a marker for a beta-lactam antibiotic resistance mechanism, which is cefepime, an inhibitor of a resistance mechanism other than said beta-lactam antibiotic resistance mechanism...

The invention relates generally to the field of analysis for example biological analysis. More specifically the invention relates to a method for the detection of at least one microorganism in a sample placed in a closed container said method essentially comprising the following steps: a) in the container bringing int...

The présent invention relates to a method for collecting the entirety or a portion of a sample ( 11) of a raw, enriched, or cultivated biological material (7) in contact with a culture médium (8), for example gélose, for example in a Pétri dish, using a probe (3) provided with one termination end (4), said sampling me...

The invention relates to a System (1) for the in vitro detection and/or quantification, by fluorometry, of at least one analyte in a sample (E) of fluid constituting a biological material, in particular for an immunological test, including a radiation source (10), followed by an optical splitter (13) for splitting...

The present invention relates essentially to a specific culture medium for growth, detection, identification and/or counting of Staphylococcus aureus bacteria, said medium being characterized in that it comprises at least one fluorogenic, chromogenic or luminescent substrate of phospholipase C. Said medium permits d...

The present invention relates in general to the field of analysis e.g. bioanalysis. More specifically the present invention relates to a method for detecting at least one microorganism in a sample said method essentially including the following steps: a) placing said sample in contact with at least one culture medium ...

The present invention provides primer or/and probe, this target sequence containing at least one variation, defined as either one non-conserved nucleotide, called genotype variation, or one nucleotide variation within one and the same genotype, wherein the primer or/and probe comprises a nucleic acid sequence that i...

The present invention provides improved tests for the detection of methicillin-resistant Staphylococcus aureus bearing a variant mecA gene. The tests are particularly useful for eliminating certain false negative results due to the presence of this variant in MRSA in patient samples

The invention relates to a method for the selective isolation of micro -organisms of interest and/or nucleic acids of micro -organisms of interest , using a) saponin , b) an enzyme solution that can lyse the free nucleic acids , and c) optionally an agent for the precipitation of the non- lysed micro -organisms of i...

The present invention relates to a device and a method for carrying out a trial to determine the presence or the absence of at least one analyte in a liquid sample the device comprising:  a) a support  b) a matrix 1 fixed on the support which allows the migration of the liquid sample said matrix comprising:  (i) a z...

The present invention relates to a method for characterizing at least one microorganism from a sample, said method including identifying said at least one microorganism and determining the properties of typing, potential resistance to at least one antimicrobial, and virulence factor, characterized in that determining ...

in vitroThe invention relates to the use of a folate derivative for an assay of the folate in a sample such as a biological sample.

The invention relates to a method for the enrichment and sélective culture of mycobacteria contained in a biological sample, in which ail or part of said sample is sown in/on a culture means comprising a nutritive component that stimulâtes the development and growth of mycobacteria, characterised in that said culture ...

Device (2) for preparing and/or treating a biological sample comprising a set of storage chambers (5) and/or reaction chambers intended to receive a fluid, said chambers (5) being separated by walls (6) so as to constitute a set of adjacent chambers. The device comprises a base (4) and a drawer (3) comprising the set ...

A method for distinguishing at least 3 groups of microorganisms in a biological sample, said sample comprising: • a first group of Gram positive bacteria, belonging to a first taxon of microorganisms and comprising at least one mechanism of resistance to an antimicrobial; • a second group of Gram positive bacteria...

A method for distinguishing at least 3 groups of microorganisms in a biological sample, said sample comprising: • a first group of yeasts, belonging to a first taxon of yeasts and comprising at least one mechanism of resistance to an antimirobial; • a second group of yeasts, belonging to a second taxon of yeasts, ...

The present invention relates to a method for determining, in vitro, the probability of a patient developing severe dengue, based on a blood sample, according to which: a) the quantity in said blood sample of at least one marker, which is olfactomedin 4, is determined, b) the quantity of olfactomedin 4 determi...

The present invention relates to a method for determining, in vitro, the probability of a patient developing severe dengue, based on a blood sample, in which: a) the quantity in said blood sample of at least one marker, which is platelet factor 4, is determined, b) the quantity of platelet factor 4 determined in step ...

The present invention relates to, among other things, a device for collecting airborne microorganisms, said device having: an air collecting module, comprising: i. an upper element having an air admission duct permitting entry of an air stream into said module, said duct being provided, at its base, with means for d...

The present invention provides improved tests for the detection of methicillin-resistant Staphylococcus aureus. The tests are particularly useful for eliminating false positive results due to the presence of a mixed bacterial population in patient samples.

The present invention concerns a method for specifically detecting and identifying Streptococcus agalactiae, using a reaction medium comprising at least one esterase enzymatic substrate.

The present invention relates to  a method for detecting  at least one target microorganism that may be present in a sample, comprising the steps of: a) bringing into contact, in a container: said sample, a medium that enables the growth of the target microorganism(s), and a cell population capable of being lysed b...

THE INVENTION RELATES TO A DEVICE (10) FOR DETECTING THE PRESENCE OF AT LEAST ONE MICRO ORGANISM IN THE CONTENTS (101 201) OF A CONTAINER (100 200) COMPRISING A WALL WITH A TRANSLUCENT ZONE SAID DETECTION DEVICE (10) COMPRISING: A) AT LEAST ONE LIGHT SOURCE (11) SUCH AS A LIGHT EMITTING DIODE (LED) ABLE TO ILLUMINATE ...

The invention essentially relates to a medium for the culture and detection of target microorganisms, comprising: at least one natural or synthetic specific substrate allowing the detection of at least one enzyme activity or metabolic activity of said target microorganisms, at least one comp...

The present invention concerns a method for specifically detecting and identifying Streptococcus agalactiae, using a reaction medium comprising at least one -glucosidase enzymatic substrate.

The invention relates to a method for preparation of non-lamellar bioresorbable microparticles to which protein substances are bonded, characterised (10) in comprising the following steps of (i) preparation of said microparticles from at least one bioresorbable polymer without stabiliser and without detergent and (i...

The invention concerns methods and compositions that can be used for detecting cancer in mammals, particularly humans. The invention particularly concerns serum markers of cancers and their use in diagnostic procedures. The invention also concerns tools and/or kits that can be used for carrying out these methods (re...

A method for dividing an analyte present in a solution and which is fixed on magnetic particles, is disclosed. It comprises sedimentation of the magnetic particles together with the separation into a plurality of residues.One of the preferred embodiments relates to: - the formation of at least a residue (22, 30) of...

Analysis chip of at least one analyte, said chip comprising at least one analysis spot for recognition and immobilization specific to the analyte; and a reference range (G) comprising several reference spots each arranged on said chip in a defined manner and independently of one another, each reference spot of this ...

The invention relates to a method tor detecting PrP in a biological human or animal sample that may contain 1YP. the inventive method is characterised in that it uses a molecule containing at least one positive charge and/or at least one osidic bond and a ligand other than a proteinic ligand selected from macrocycli...

(57) The invention relates to novel enzymatic substrates with the following formula: (I) where Rb R2, R3, R4, R5, R6, A and X are as defined in claim 1, the reaction media comprising the same and the use thereof for the detection and/or identification and/or quantification of microorganisms expressing at least o...

The present invention relates to a single-layer polymer film, intended to be used for packaging articles having an extended shelf life, said film being composed of a cast polyamide sheet, covered, on one of its faces, with a heat-sealable coating, comprising polyvinyl chloride (PVC) and/or polyvinylidene chloride (P...

The invention relates to a method for detecting and/or identifying E. coli in a urine sample, that comprises: a) inoculating the urine sample liable to contain E. coli on a detection medium that comprises a first substrate selected from a beta-glucuronidase substrate, beta-galactosidase substrate and alpha-galact...

The invention relates to a detection medium comprising: o  a substrate for a metabolic activity specific for a group of Gram-negative bacteria; o  a beta-glucosidase or cellobiosidase substrate; o a beta-glucosidase or cellobiosidase inducer, said inducer being a carbohydrate constituted of a carbohydrate linked ...

A medium for detecting and/or identifying Escherichia coli (E. coli) in a biological sample, wherein the said medium comprises: tryptophan and a substrate for an enzyme A, expressed by the majority of E. coli,; and wherein the said medium is   inoculated with the biological sample liable to contain E. coli in ord...

The present invention relates to a method for placing a receptacle (1) in a device for sampling liquid (3). It also consists of a device for sampling a liquid (3) present in the receptacle (1), enabling the method of placing said receptacle (1) to be applied. This method consists in placing the receptacle (1), such...

The present invention relates to a system for temperature control within an automatic biological analyzer, the automatic analyzer essentially comprising: • support, guidance, and step-by-step transport means for reaction cuvettes on a path comprising a predetermined number of positions, • a support turnta...

The present invention relates to a method for identifying at least two groups of microorganisms expressing the same enzymatic activity, comprising the following steps: a) incubating said groups of microorganisms in a reaction medium comprising a first enzyme substrate and a second enzyme substrate, said first and s...

The invention concerns novel enzymatic substrates of the general formula below: wherein : R1, R2 R3, R4, R5, R6, A and X are as defined in claim 1, reaction media containing same and their use for detecting and/or identifying and/or quantifying microorganisms expressing at least one peptidase activity. Appli...

The present invention concerns a method for specifically detecting and identifying Streptococcus agalactiae, using a reaction medium comprising at least one esterase enzymatic substrate.

The present invention relates to a method for the in vitro diagnosis of the exclusion of acute coronary syndromes (ACS), consisting in associating the quantification of the concentration of at least one cardiac marker selected from troponin, CK-MB and myoglobin and the quantification of the concentration of D-dimers...

The present invention relates to a reaction medium for identifying/detecting microorganisms, that comprises at least one active molecule encapsulated in a cyclodextrin.

The present invention relates to an enzyme substrate for detecting nitroreductase activity of formula (I) below: in which: • X is S,NXl,O or NXl-CO; • Rl is nothing or a substituent selected from C1, CH3, Br, F, I, alkyl, aryl and carboxyl; • R2 is nothing or a substituent selected from C1, O-CH2-O, O-CH3, F, d...

BIOMERIEUX S.A. The present invention relates to a double pair of oligonucleotides for amplifying two target sequences located, respectively, in the H5 and Nl genes of the genome of the Influenza A virus, said oligonucleotides being of a length ranging between 10 and 50 nucleotides and comprising at least one fragm...

The present invention relates to an enzyme substrate for detecting peptidase activity in microorganisms, of formula (I) below: in which: □  X is S;NXl;O;or NXl-CO; □ Rl is nothing or one of the following substituents: C1, Br, F, I, OH, or an alkyl, aryl or carboxyl group; □ R2 is nothing or one of the following ...

The invention relates to the use of a combination of two culture media for distinguishing at least three groups of microorganisms in a biological sample, comprising: • a first group of microorganisms, belonging to a first taxon of microorganisms and comprising at least a first mechanism of resistance to a first tr...

Method for controlling the progress of a liquid in a microfluid component The method for controlling the progression of a fluid, from upstream to downstream, in a microfluidic component comprising for example a plurality of microchannels each comprising a plurality of successive reaction or detection zones and a pl...

The invention relates to a reaction medium for Vibrio group bacteria cholerae (cholerae/vulnificus and mimicus) and Vibrio parahaemolyticus comprising: a substrate enabling the detection of a ß-galactosidase enzymatic activity; a sugar, and; a colored indicator. The invention also relates to the use of this medium f...

The present invention relates to a device (10) for automatic pipetting of a liquid specimen, essentially comprising: a) at least one means (16) for sampling-dispensing the liquid specimen; b) at least one compartment for receiving the liquid specimen, intended to receive all or part of the liquid specimen s...

The invention relates to a reaction medium for the culture and/or detection and/or identification of bacteria of the Legionella genus, including at least one siliceous compound, characterized in that said siliceous compound is a nonpolar silica. The invention also relates to the use of a reaction medium including at...

The invention relates to a method for isolating microorganisms on an agar culture medium, including the steps of: depositing, on said agar culture medium, a predetermined amount of a sample to be analyzed and optionally containing said microorganisms or a suspension of said microorganisms; applying a seeding me...

A method for distinguishing at least 3 groups of microorganisms in a biological sample, said sample comprising: • a first group of microorganisms, belonging to a first taxon of microorganisms and comprising at least one mechanism of resistance to an antimicrobial; • a second group of microorganisms, belonging to a...

The present invention relates generally to the field of analysis, for example biological analysis. More specifically, the present invention relates to an analysis device (10, 40, 501, 60) designed to be 10 associated with a container (22, 50, 70) containing a sample (28) to be analyzed, said device comprising ...

The present invention relates to a cartridge which can be positioned inside an air collection means and receive a means for recovering nucleic acids, said cartridge being substantially cylindrical and comprising a microorganism retaining zone, said retaining zone comprising microorganism lysis means. The invention a...

The invention relates to a peptide domain required for interaction between the envelope of a virus pertaining to the HERV-W interference group and an hASCT receptor, comprising an N end point and a C end point. Said peptide domain is defined, at the N end point thereof, by a pattern formed by the amino acids L (Z)α-...

The present invention relates to a reaction medium for detecting and/or identifying methicillin-resistant Staphylococcus aureus (MRSA) bacteria, comprising a chromogenic substrate, a first antibiotic which belongs to the cephalosporin family and a second antibiotic which belongs to the aminoglycoside family. ...

The present invention relates to the use of at least one fluoroalkyl surfactant and of at least one alcohol comprising from 1 to 4 carbon atoms for dissociating vitamin D and/or a vitamin D metabolite from vitamin D binding protein and also to a solution comprising at least one fluoroalkyl surfactant and at least on...

The present invention is part of the field of microbiology and microorganism culture. It relates more specifically to proposed alternative solutions to conventional agar culture media. In this context, it proposes a microbiological culture device comprising: - a component made of an absorbent material which ...

The present invention relates to a reaction medium for detecting and/or identifying Staphylococcus aureus bacteria, comprising a combination of two enzymatic substrates for alpha-glucosidase.

The present invention relates to a reaction medium for detecting and/or identifying Methicillin-resistant Staphylococcus aureus (MRSA) bacteria, comprising a predetermined combination of two antibiotics, a first antibiotic which belongs to the cephalosporin family and a second antibiotic, said first and second antib...

The present invention relates to a method for the quantitative detection of a target protein in a sample, in which the second-generation fragment ions are detected for providing a series of, quantitative measurements, at least one of which is correlated to the amount of proteotypic peptide generated and to the amoun...

The invention relates to a method for detecting identifying and enumerating micro organisms in a porous support comprising the powder of a reaction medium throughout the entire thickness thereof said support having been dry impregnated throughout its entire thickness with a dehydrated reaction medium. The inventio...

The present invention concerns a bi epitope compound of formula I: in which: E1 and E2 identical or different each separately represents a peptide sequence comprising at least one epitope of an analyte; X and Y identical or different each separately represents a linking arm  the carrier molecule is soluble and Z rep...

The present invention relates to polypeptides of the ORF2 protein of the hepatitis E virus including at least the amino acid sequence 394-660, numbered in relation to an ORF2 protein of 660 amino acids, in which three cysteines at positions 627, 630 and 638 have been mutated or, for an ORF2 protein of different leng...

The present invention relates to an end fitting capable of being fitted to the body of a manual or automated device for sampling biological material of microbial origin comprising: a) a distal end comprising a means for sampling biological material of microbial origin b) a proximal free end intended to come into con...

A method for suspending the analytes contained in a blood sample previously dried on blotting paper wherein blotting paper is provided on which a blood sample with an initial volume greater than or equal to 100 µL is dried the blotting paper having a sample absorption capacity of at least 60 µL·cm-2 and a basis weig...

The invention relates to a device (1) for determining the presence of a contamination of microorganisms in a fluid, said device (1) comprising a casing (2) comprising an inner volume, a cover (3) closing the casing, a fluid inlet port (11), at least one filtration member (4), at least one nutritive layer (5) compris...

The present invention relates to a method of amplification and/or of detection for removing contaminants in a liquid biological sample containing nucleic acids of interest that we wish to amplify, said method comprising the following stages: a) treating the biological sample chemically or enzymatically to permit co...

The invention relates to the field of diagnostics or prognosis. It particularly relates to immunoassay compositions comprising at least (i) an amphipol and (ii) a (meth)acrylate monomer-based amphoteric copolymer some of said monomers comprising a phosphorylcholine group. The disclosed compositions are useful in par...

The present invention relates to a method for preparing mammalian anti-AMH antibodies comprising the steps of: (i) immunising an animal with a polypeptide of AMH or a polynucleotide coding for this polypeptide of AMH said polypeptide of AMH comprising at least the 99 amino acids of sequence SEQ ID N°1 or of a sequen...

The invention relates to a microbiological testing device (10) for testing a liquid to be analysed that may contain at least one microorganism said device comprising: - an enclosed internal space (12); - a microbiological filtration means (32); - an inlet port (40) characterized in that the device (10) comprises a n...

It is disclosed a method for performing fluorescence measurement on a sample, comprising: Illuminating the sample using a light source, acquiring at least one fluorescence image of the illuminated sample, and processing the fluorescence image to determine a fluorescence intensity of the sample, characterized in that...

The invention relates to the field of molecular biology and more particularly that of clinical and industrial microbiology. More specifically, the present invention relates to a culture medium for detecting microorganisms, comprising, as a gelling agent, a mixture of agar and kappa-carrageenan. ...

The invention concerns compounds of formula (I) and their salts, as defined into claim 1 and their uses, in particular in PCR applications.

The invention relates to a microbiological typing method, which comprises providing: a database of genetic profiles of microbial strains; and a phylogenetic tree of assignments of the genetic profiles to positions in the phylogenetic tree, and of frequencies of variation of the profiles in the tree. The typing of a ...

The invention relates to a microbiological typing method, which comprises providing a database of genetic profiles of microbial strains, a phylogenetic tree, assignments of the genetic profiles to positions in the phylogenetic tree, and frequencies of variation of the profiles in the tree. The typing of a microorgan...