A process for producing a layered lithium manganese nickel cobalt oxide material includes producing a raw layered lithium manganese nickel cobalt oxide ( LMNC ) material. Optionally a dopant capable of enhancing the performance of the layered LMNC material when used as a cathode material in an electrochemical cell i...

The present invention relates to 6-aryl-4-phenylamino quinazolines of formula I wherein, R and R" are as herein described. The present invention particularly relates to synthesis and anticancer and phoshpoinositide-3-kinase-a (PI3K-a) inhibitory activity. In addition, the invention relates to methods of using com...

The invention relates to a system for monitoring the condition of elongate structural elements and more particularly but not exclusively to a system for monitoring and detecting cracks and breaks in railway rails. The invention furthermore extends to the methodology of designing and developing such a system. The met...

The invention relates to a hologram or holographic intensity data processing method and system. The system implements the method which comprises receiving holographic intensity data comprising at least a holographic intensity pattern or image at a discrete location in a propagation space the propagation space compri...

A cell proliferation apparatus for the automated culturing of cells, the proliferation apparatus including a bioreactor having contained therein a stimulus-responsive three dimensional (3D) cell scaffold, the stimulus-responsive three-dimensional (3D) cell scaffold being operable reversibly to change its surface pro...

A method of fabricating an artefact (15) includes treating natural fibres (1 10) with a non halogenated flame retardant agent (120) the fibres (1 10) also being treated with a smoke suppressant (120). At least one pre preg is formed (170 180) from the treated natural fibres and from a resin composition (160) includi...

The invention provides compounds of formula A or B which are useful in the treatment of a subject infected with HIV.

A process for producing a lithium manganese oxide spinel material includes producing a raw lithium manganese oxide ( LMO ) material by means of combustion synthesis; optionally subjecting the raw LMO material to microwave treatment to obtain a treated material; annealing the raw LMO material or the treated material ...

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A method for assessing the integrity of a rock mass, the method including impacting the rock mass, capturing an acoustic signal generated as a result of the impact, deriving a frequency distribution for the captured acoustic signal, processing data from the frequency distribution by means of a neural network process...

A method of producing a flagellin-based chimeric protein includes culturing a B. halodurans BhFD05 (∆hag, ∆fliD, ∆wprA, ∆alp, ∆apr, ∆vpr, ∆asp) strain deposited under Accession Number 41533 at the NCIMB. The strain is caused to express and secrete high levels of a flagellin-based chimeric protein into an extracellul...

A method for manipulating a nucleoside includes converting guanosine to 5-methyluridine by means of biocatalytic transglycosylation. The biocatalyst comprises a combination of a purine nucleoside phosphorylase from Bacillus halodurans, PNPase (BH1531) of sequence ID No 1, or a protein with at least 90% sequence simi...

A method of encapsulating a pharmaceutical active includes dispersing a matrix former into at least one of a water phase and an oil phase with the pharmaceutical active being present in at least one of the oil phase and the water phase and with the oil phase comprising a vegetable based edible oil. An emulsion is fo...

The invention relates to an apparatus method and system for measuring and optionally detecting an electrical discharge having a discharge magnitude wherein the electrical discharge causes a corresponding emission of optical radiation. The apparatus embodies the system and method in accordance with the invention wher...

The invention provides a process for the production of nanoparticle carriers for drug delivery, said nanoparticles being produced by preparing a double emulsion of water-oil-water including one or more polymer which forms the basis of the nanoparticle carrier, blending the drug to be delivered into one of the emulsi...

The invention provides crystalline Ti powder produced in molten salt medium  said powder comprising predominantly particles of single a-Ti crystals that are directly applicable in powder metallurgy. The invention extends to process for production of titanium powder in molten salt medium including steps of reacting i...

The invention provides a process for the production of crystalline titanium powder containing single crystals or agglomerates of single crystals having an average crystal size (by volume) greater than 1 µm said process including reacting a titanium chloride species preferably titanium dichloride and reducing metal i...

The invention provides f lagellin-based fusion proteins (FBFP) useful for a variety of purposes, in bioremediation to remove metal ions from a liquid, to express an enzyme or an immunogen, nucleic acids encoding the FBFP, vectors containing the nucleic acids, and host cells harboring the vectors. Furthermore, the ...

The invention provides a process for hydrolytically converting aloeresin A to aloesin by the following reaction: The amount of aloesin available for extraction from sap of aloe plants is thereby increased and the extraction and purification of the aloesin is also made easier and less costly. As aloesin is more comm...

The invention provides the use of at least one plant selected from plants of the family Zingiberaceae in the preparation of a medicament for use in the treatment or prophylaxis of allergic diseases. The plant is optionally selected from the genera Siphonochilus, Kaempferia, Cienkowskia and Cienkowskiella and the spe...

Methods of screening and designing compounds as inhibitors of glutamine synthetase, including adenylylated glutamine synthetase, are provided herein. Compounds and compositions useful for the treatment, prevention, and/or amelioration of bacterial infections, including Mycobacterium tuberculosis, are also provided. ...

A process for the production of a substance or composition for the therapeutic or prophylactic treatment of erectile dysfunction or the enhancement of libido in a male human or animal subject comprises the step of formulating the substance or composition from at least one of plant material and an extract of plant ma...

An emulsion-derived particle comprises a lattice of polymeric strands cross-linked by means of a cross-linking agent, and interstitial openings adjacent and around the strands. Functional groups are provided on the lattice and proteins and/or modified proteins can react with these, thereby to be bonded to the lattic...

A composition from which a coating or film can be formed comprises at least one prolamin protein, gluconic acid and/or a giuconic acid derivative as a plasticizer, and a solvent for the protein and the plasticizer. The composition is in the form of a solution.

The invention provides isolated Y. lipolytica cells and substantially pure cultures of Y. lipolytica cells containing exogenous nucleic acids encoding EH polypeptides, e.g., enantioselective EH polypeptides. Also featured by the invention are methods for the production of the EH polypeptides and methods for hydrolys...

A pharmaceutical composition contains an extract obtainable from a plant of the genus Trichocanion or Hoodia containing an appetite suppressant agent having the formula A process for obtaining the extract and a process for synthesizing compound (1) and its analogues and derivatives is also provided. The inventio...

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The invention provides a method of encapsulating an active substance in an interpolymer complex, to make an encapsulated product in particulate form.The method comprises forming a mixture of a supercritical fluid, an interpolymer complex and an active substance and then causing or allowing the interpoilymer compl...

The invention provides a method of encapsulating an active substance in an interpolymer complex, to make an encapsulated product in particulate form. The method comprises forming a mixture of a supercritical fluid, an interpolymer complex and an active substance and then causing or allowing the interpolymer complex ...

Methods of screening and designing compounds as inhibitors of glutamine synthetase are provided herein. Compounds, e.g., serine protease inhibitors, and compositions comprising the same, that are useful for the treatment, prevention, and/or amelioration of bacterial infections, including Mycobacterium tuberculosis, ...

A soft tissue bulking material includes a plurality of particles. Each particle comprises a rounded polymeric shell defining an internal cavity and having a maximum outer dimension of 50μm - 250 μm. A port or opening is provided in the shell. The port or opening thus provides access to the cavity. The port or ope...

The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific internal epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, vectors containing such nucleic acid molecules, and cells containing such vector...

Yarrowia lipolyticaY. lipolyticaY. lipolyticaThis invention relates to a method for the production of proteins preferably heterologous proteins under the regulation of the hp4d promoter in . In particular this invention describes a method for manipulating the growth rate of by regulating the carbon and/or nitrogen s...

A method of upgrading a titaniferous material includes nitriding and reducing a titaniferous material which includes T1O2 and Fe oxides in the presence of nitrogen and carbon to convert the T1O2 to TiN and to reduce most of the Fe oxides to Fe. The Fe is oxidised in preference to the TiN to form Fe + ions, wher...

A process for producing enzyme structures includes providing an emulsion of droplets of a first liquid phase dispersed in a second liquid phase. The one liquid phase is a hydrophilic phase, while the other liquid phase is a hydrophobic phase which is immiscible with the hydrophilic phase. Enzyme molecules are locate...

The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific meso-epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, vectors containing such nucleic acid molecules, and cells containing such vectors. A...

The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospeciflc styrene epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, vectors containing such nucleic acid molecules, and cells containing such vectors...

The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific 2,2-disubstituted epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, vectors containing such nucleic acid molecules, and cells containing su...

The invention relates to a system and method of analysing material as well as to an apparatus for analysing material particularly though not necessarily exclusively biomaterial. The invention entails receiving holographic intensity data comprising at least a holographic intensity pattern associated with a sample of ...

The invention comprises an oligonucleotide selected from the group comprising SEQ ID NO: 1 SEQ ID NO: 2 SEQ ID NO: 3; SEQ ID NO: 4; SEQ ID NO: 5 and SEQ ID NO: 6. The invention also comprises a complementary oligonucleotide of the oligonucleotide selected from the group comprising SEQ ID NO: 1 SEQ ID NO: 2 SEQ ID NO...

A liquid flame retardant composition is in the form of an admixture which includes a phosphate based flame retardant ammonium hydroxide and zinc borate. The invention extends to a method of providing a phosphate based liquid flame retardant composition to the use of a phosphate based flame retardant ammonium hydroxi...

This invention relates to a process for producing an isotactic polypropylene based composite, comprising: reactive blending of isotactic polypropylene homo-polymer; polypropylene grafted with a carboxylic anhydride or a furan type moiety such as maleic anhydride grafted polypropylene; and an amino silane such as (3-...

This invention related to a method of and system for detecting a threat particularly a threat to a vehicle associated with an explosive blast and/or detonations. The method typically comprises receiving electromagnetic signals or data indicative thereof via a suitable electromagnetic detector arrangement from a targ...

A pharmaceutical composition contains an extract obtainable from a plant of the genus Trichocaulon or Hoodia containing an appetite suppressant agent having the formulaA process for obtaining the extract and a process for synthesizing compound (1) and its analogues and derivatives is also provided. The...

A field effect transistor comprising a source including a plurality of electrode projections with spaces in between. A drain includes a plurality of electrode projections each located in one of the spaces between the electrode projections of the source thereby forming a drain-source electrode connection area of al...

An ex vivo method of analysing a biological sample comprising a plurality of label-free cells to determine whether or not the sample includes cells that are infected by an infective agent includes optically trapping a label-free cell in the biological sample with an optical beam and spectroscopically investigating t...

A vascular compression device with multi-axis four degree of freedom in two translational and two rotational motion for achievement of hemostasis after an interventional procedure by application of compressive pressure on a patient’s incision site is presented. Functionally, the apparatus enables easy manipulati...

Title: ADVANCED INORGANIC - ORGANIC GEOPOLYMERIC CORROSION PROTECTIVE COATING MATERIAL FOR MILD STEEL The present invention provides Advanced inorganic - organic geopolymeric coating material for mild steel utilizing fly ash, sodium hydroxide, sodium silicate, iron oxide red, silica fume , water, epoxy resin and ...

A method of recycling or processing layered packaging material includes admixing a polymer-metal composite obtained from or forming part of layered packaging material with a reactant selected to react with the metal of the polymer-metal composite at elevated temperatures, and reacting the polymer-metal composite wit...

The present disclosure discloses a nickel catalyst of formula (I). The present disclosure also discloses a process of hydrogenation-dehydrogenation coupling catalyzed by catalyst of formula (I). Further, the present disclosure also discloses a process for secondary imine hydrogenation reactions catalyzed by catalyst...