A process of preparing an extract of annona squamosa comprising collecting leaves of annona squamosa; drying the said leaves; preparing an aqueous extract of the leaves at a temperature of 80-100° C; filtering the extract to remove the solid material, concentrating the extract at temperature range of 30 to 40° C und...

A DNA construct comprising a silencing vector derived from a virus which induces the silencing of an endogenous gene when introduced into plants.

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A multifunction interface device for use, inter alia in conducting a pluarilty of laboratory experiments comprising one or more signal generation means responsive to a sensor means provided on an experiment set up in order to generate signals indicating a specific result required or obtained therefrom in machine rea...

The present invention relates to an improved multiplex PCR-based process for detecting Chalamydia Trachomatis and Neisseria Gonorrhoeae. Further related to a primers and probes useful in detection of various sexually pathogens like bacteria, fungi and virus by multiplex PCR reaction followed by visual detection m...

The present invention relates to compositions for developing latent impression marks on any surface of an article. The composition comprises of at least one dye, at least one inorganic compound having crystal unit cell volume from 250 A or more and at least one adhesive agent.

The present invention relates to method for treating mycobacterial  infection/disease by administration of a therapeutically effective amount of compound of formula I

The present invention relates to thionated cinnamate compound of formula I and process for preparation thereof:wherein M represents or orC=C; X represents O or S; Y represents OR7, SR7 or NR8R9; R1-R6 each independently represents H, (CH2)nOH, (CH2)nSH, (CH2)„halogen, alkyl, (CH2)naryl, (CH2)nOalkyl, (CH2)nSalk...

The present invention provides N-protected isatin compounds of following formula I: wherein X independently represents O, S, NR1; Y represents O, S; R1 represents H, alkyl, aryl; R2 – R8 independently represents H, (CH2)nhalogen, alkyl, (CH2)naryl, (CH2)nOH, (CH2)nSH, (CH2)nOalkyl, (CH2)nSalkyl, (CH2)nOa...

The present disclosure relates to a process of constructing a phage display library enriched for recombinant phages having in-frame protein encoding DNA fragments (ORF), by employing a modified helper phage comprising at least one protease cleavage site in the polynucleotide encoding gIII protein, this renders th...

Title: A method of transient expression of gene of interest in plants using a plant DNA virus based vector. Two DNA constructs comprising the transient gene expression vectors based on the DNA-B of a plant DNA virus, wherein a reporter gene coding sequence flanked by two MCS replaces the BCI ORF in one and the B...

The present invention relates to an Insulator construct for controlling leaky expression of a lethal gene from enhancing functions of a strong constitutive promoter present in the said Insulator construct following integration into the genome of a plant.

The present invention relates to a process for the extraction of Psoralen from in vitro grown tissues of Psoralea. The Psoralen obtained by the process of the present invention is in the range of 1500-2600 µg/g fresh wt. in seeds; in the range of 200-500 µg/g fresh wt. in leaves, nodes and roots; and in the range of...

The present invention relates to cloning, expression in E coli and purification of mycobacterial antigens. The invention also in particular relates to expression and purification of two important mycobacterial proteins with serodiagnostic potential, namely, 38-kDa and Mtb81 antigens, in monomeric form which involves...

"A process for the preparation of a pH responsive polymer which can be used as a coating material for micro/macro capsules, particles intended for delivering drugs preferentially to the colon". This invention relates to a process for the preparation of a pH responsive polymer which can be used as a coating material...

This invention relates to a process of producing organic/inorganic/polymeric and metal nanoparticles in a water in oil system comprising steps of dissolving a 0.025M-0.2M of a surfactant in an oil to obtain reverse micelles, adding an aqueous solution of polymers/monomer with initiators/precursors to the reverse mic...

The process of preparing thermoactive alkaline lipase from lipolytic strain of Burkholderia multivorans, said process comprising the steps of: isolating lipolytic strain of B. multivorans from compost, culturing the said isolated B. multivorans in nutrient source, separating lipase by conventional methods, purifying...

The present invention relates to a composition for dehairing of hides comprising an enzyme and a peptide in the ratio of 0.1: 6.

This invention relates to a process for the synthesis of bisbenzimidazoles and its derivations comprising reacting 5 chloroaniline with zinc dust and acetic anhydride to produce 5 chloroacetanilide; reacting 5 chloroacetanilide with HNO3 to produce 2-nitro-5- chloroacetanilide; boiling sodium methoxide and 2-nit...

The present invention provides a recombinant BCG over-expressing α-crystallin protein for use in generating an immunogenic response in a subject against Mycobacterium and a vaccine formulation comprising the recombinant BCG. The invention further provides a prime boost vaccination approach against the Mycobacterium ...

The present invention provides a process for the regioselective acylation of nucleosides, said process comprising preparing solution of a nucleoside, an acylating agent and a lipase; subjecting said solution to incubation at a predetermined temperature and filtering off the enzyme to obtain the product. ...

This invention relates to dihydropyrimidinone compounds for the treatment of cardiovascular diseases and a process for preparing the same.

The present invention relates to identification, isolation, characterization and use of a novel gene OSISAP1 obtained from rice and its corresponding novel protein sequence; also relates to a method of over-expressing the novel gene OSISAP1 encoding a zinc-finger stress associated protein from rice conferring salt, ...

The present invention provides a novel speedy and efficient process for the isolation and purification of sesquiterpene compounds from a Curcuma plant. Medicinal plants have contributed enormously to the identification of lead compounds in drug discovery programs. Curcuma longa known as 'Turmeric' in English, 'Ukon...

A PCR based prototype kit for detecting Chlamydia trachomatis and Neisseria gonorrhoeae comprising: a transport medium for sample collection solution A & B, a reaction mixture having the primers for Chlamydia trachomatis & Neisseria gonorrhoeae, a gel loading dye, Agarose gel, gel running buffer and a DNA marker lad...

This invention relates to a the compound represented by general formula I. a known antimalarial, anticancer pharmacophore, and a pharmaceutical composition comprising the compound represented by the formula (I) a salt thereof, a solvate thereof, or a prodrug thereof; in combination with one, two or more kinds select...

In producing diastatic and proteolytic enzymes for use in bread-making by cultivating a fungus, especially Aspergillus oryzae, on a cereal medium such as hominy boiled in water, acid is added to the culture medium to inhibit the growth of organisms which produce "ropiness." The invention is particularly described wi...

The present invention provides a restorer (Rf) gene for the 'Polima' cytoplasmic male sterility in Brassica campestris (synonymus Brassica rapa) plants, and to a method of producing restorer lines in Brassica campestris. The invention further reveals that the restoration of 'Polima' CMS in B. campestris is controlle...

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The present invention relates to compounds of Formula I wherein- X and Y represent O, S, NR"; Rnrepresents alkyl, aryl, OR1, NH2, OR1, NR1R2; wherein Rl, R2 - H, alkyl, phenyl, aryl, OCOR3, SCOR3, NHCOR3, NR1COR3, etc. (wherein R3 represents alkyl, phenyl, aryl, heteroaryl); R" and R" represent H, alkyl, phenyl, su...

The present invention relates to the novel compounds of formula I having inhibitory effects on cytokine-induced cell adhesion molecule ICAM-1 expression onto human endothelial cells anti-inflammatory activity, used for treating one or more diseases caused by cell adhesion and /or cell infiltration selected from the ...

The present invention relates to recombinant BCG-Ag85C based immunization against TB. The invention also provides a method for developing a recombinant BCG strain that over expresses Ag85C (fbpC, Rv0129c) gene of Mycobacterium tuberculosis and also provides a method to assess the protective efficacy of recombinant M...

The present invention provides nutritional compositions essentially comprising all natural ingredients, said nutritional compositions being rich in energy, macronutrients, micronutrients and fiber and at the same time palatable for providing overall nutrition rich for maintaining and improving health. The invention ...

The present invention provides a solar water distillation apparatus which provides high grade distilled water which can be utilized as a source of clean, hygienic and safe drinking water, especially in areas where water is contaminated. The solar water distillation apparatus comprises a top chamber, a plurality of d...

The present invention relates to polymer films or coating materials and methods for preparing the same. The polymer film or the coating material comprises of at least one biopolymer, at least one synthetic polymer, and at least one antimicrobial agent.

The present disclosure is directed to a process for producing aromatic carboxylic acids by oxidation of methyl arenes in the presence of an oxidation reaction medium containing water and a heterogeneous catalyst. The heterogeneous catalyst is a cerium oxide nano-particulate catalyst with controlled morphology hav...

A process for designing of PCR-based detection method for chlamydia trachomatis comprising designing of PCR primers from the genome sequence of C. trachomatis selecting DNA sequence of genes for PCR based diagnostic of C trachomatis, optimizing the PCR conditions of the PCR primers; subjecting the said genes and pri...

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This invention relates to a process for the synthesis of bisbenzimidazoles and its derivations comprising reacting 5 chloroaniline with zinc dust and acetic anhydride to produce 5 chloroacetanilide; reacting 5 chloroacetanilide with HNO3 to produce 2-nitro-5- chloroacetanilide; boiling sodium methoxide and 2-nitro-5...

This invention relates to a process for producing a targeted gene and/or drug delivery system for liver cells comprising the steps of chemical reduction of Sendai virus for reduction of HN protein; subjecting the reduced virus to the step of dialysis for removal of the reducing agent; solubilizing the reduced virus ...

The invention relates to aminoquinoline based hybrids and uses thereof, comprising of 4-aminoquinoline, 8-aminoquinoline, mefloquine, amidoquine& all combinations thereof, with general formula (I) as herein described: (Formula Removed) Formula (I) Wherein R is independently absent or selected from the group of sub...

The present invention relates to a method for preparing an Insulator construct for controlling leaky expression of a lethal gene from enhancing functions of a strong constitutive promoter present in the said Insulator construct following integration into the genome of a plant and a method for development of ...

The present invention describes a method of producing infection in okra plants with okra enation leaf curl virus (OELCuV), using an efficient agrobacterium-mediated inoculation method with cloned viral DNA. The invention describes the process by which viral and satellite DNAs, which accompanies the virus in plants, ...

Provided herein is a method to screen and identify test compounds that can restrict the trans-cellular propagation of the neurotoxic tau aggregates. The method involves feeding Drosophila flies with food supplemented with the test compound(s). The treated Drosophila flies are de-capitated and section of the heads im...

ABSTRACT The present disclosure relates to a triazole-based spiro-oxindoles based chemical compound (200) and derivatives thereof and a method (400) for the synthesis thereof, as shown below. wherein R1= H, CH3, F, Cl, Br, NO2, OCH3; R2= CN, COOC2H5; R3= CH3, C2H5, C3H8; and R4= CH3, C2H5, COC6H5, CH2CH2...

ABSTRACT The present disclosure relates to a therapeutic target for treatment of Rheumatoid Arthritis (RA). The target includes a G-protein ARL15 downregulated to reduce redness and inflammation in RA. A monoclonal antibody targets ARL15 to obtain ARL15mAb. The ARL15mAb does not follow TNF pathway. The ARL15mAb neg...

ABSTRACT BIOLOGICALLY ACTIVE ANTI-CANCER COMPOUND AND DERIVATIVE THEREOF, AND GREEN SYNTHESIS THEREOF The present disclosure relates to a biologically active ant-breast cancer compound (7) and derivative thereof. The compound (7) is an anti-cancer agent to inhibit breast cancer cells proliferation. The targeted br...

The present disclosure discloses a small-interference (si) RNA sequence that targets Arl15 gene to combat RA as set forth in SEQ ID No. 1. The sequence is administered twice in a week intravenously to the subject to combat RA. The present disclosure also relates to a method to alleviate symptoms of RA by downregul...

The present disclosure relates to mesoporous bioactive glass nanoparticles in which phosphorus pentoxide (P₂O₅) is partially substituted with silver oxide (Ag₂O). The nanoparticles comprise silica (SiO₂) in the range of 55–65 wt%, calcium oxide (CaO) in the range of 30–40 wt%, and a combined amount of P₂O₅ and Ag₂...