In present invention, an improved version of WEDM is developed to enhance the surface characteristics of pure Ti. Initially pure Ti is processed by WEDM using de-ionized water as a dielectric. The value of discharge energy is large in this phase i.e. rough cut setting is used to process pure Ti. In the second phase ...

Process for synthesis of Chalcones and Uses thereof The present invention relates to provide an extremely simple, rapid and high yielding practical synthetic approach for a variety of chalcones using of p-toluenesulfonic acid (p- TSA) as an efficient catalyst for the synthesis of chalcones under solvent-free cond...

Process for Novel 2-(3,5-dimethvl-1H-pvrazo1-1-vl)-l-arvlethanones as DNA photocleavin~A gents The present invention discloses the regioselective synthetic approach to novel 2-(3,5- dimethyl-I H-pyrazol- I -yl)- 1 -arylethanones under facile and extremely mild solvent free conditions. Among a series of compounds...

The present invention discloses anticancer screening of some pyrazole based compounds, against colon (HCTI 16 and HT29), prostate (DU145) and ovarian (SKOV3) cancer cell lines. The compound 2-(3,5-Dimethyl- 1 H-pyrazol- 1 -yl)- 1 -(naphth-2-y1)ethanone was found to be cytotoxic to all the cancer cell lines, excep...

The present invention discloses a rain water harvesting umbrella with water purifier and bottle attachment for getting safe drinking water from rain water. The device is a normal umbrella (Fig 1) with simple modification. The upper surface of umbrella (1) is used to collect rain water and the hollow tubular vanes (3...

In present work, a comparative experimental study has been presented on rough cut, trim cut using distilled water and trim cut using Al and Si metal powders in dielectric fluid for WEDM of Nimonic-90. Firstly, the influence of discharge energy in rough cut has been evaluated for machining rate (MR) and surface ro...

The invention provides a straw harvester including a cutter reel that cuts straw from the ground. This cut straw is then fed through a feeding conveyor with help of an auger to a chaff-cutter. Chaff-cutter contains multiple blades that helps in chaffing the cut straw which could be then collected or spread again on ...

An Optically Concentrated Solar Fluid Heater comprises an insulated tube arrangement 13, in spiral volute form to facilitate natural convection, as well as to accommodate maximum number of convex lens units at limited space and enhanced residing period for circulating fluid. Array of convex lens units 26 are mounted...

The present invention discloses a herbal pharmaceutical preparation for the therapeutic and prophylactic management of the neurological disorders including epilepsy and other seizure related neurological disorders. The herbal composition comprises of extracts or compounds of Ricinus communis, Wrightia arborea,Calend...

The present invention relates to a method and system for automatically controlling the water flow in farming lands using an internet of things (IoT). To start with, the method and system transmits a plurality of predefined rules/patterns received from a user to an IoT server (108) and further to a main control unit ...

The present invention describes the synthesis and characterization of novel peptoids under simple reaction conditions with no catalyst via multicomponent approach. The synthesized compounds (peptoids) may exhibit very good biological activity and would be used as potential candidates in the field of drug discovery a...

In heterocyclic chemistry, 4-formylpyrazoles are one notable examples of having important applications in the field of medicinal chemistry. They act as important precursors or intermediates for synthesis of several heterocyclic compounds of biological interest and drugs. This invention describes a very efficient and...

The present invention discloses the synthesis and anticancer screening of the new compounds, (E)-4-(2-(4-Chloro-3-(trifluoromethyl)phenyl)hydrazono)-5-methyl-2-(4-phenylthiazol-2-yl)-2,4-dihydro-3H-pyrazol-3-ones against lung (A549) cancer cell line. All the compounds inhibited the proliferation of A549 cells in con...

The present invention discloses the anticancer screening of the new compounds of 2-(Bromosubstituted arylamino)-4-arylthiazoles against lung (A549) cancer cell line. All the compounds inhibited the proliferation of A549 cells in concentration dependent manner. The compound 2c showed the highest anti-proliferative ac...

The present invention reported the development of new 3-Methyl-4-(3'-methylisoxazol-5'-yl)-1-aryl-1H-pyrazol-5-ol derivatives as anti-lung cancer agents. Eleven compounds from the series 5a, 5c, 5e, 5f, 5h, 5i, 5j, 5l, 5m, 5n, 5o were found to be more potent than the standard drug, Carboplatin against the lung cance...

4-Nitroazoles have a wide range of industrial, agricultural and pharmaceutical applications. They also possess biological activities like anticancer, antibacterial, radiosensitizer, antitubercular etc. This invention describes an efficient, greener and solvent free method for the synthesis of 2-(3,5-dimethyl-4-nitro...

The present invention describes the synthesis of sixteen derivatives of 3-Methyl-4-(3'-methylisoxazol-5'-yl)-1-aryl-1H-pyrazol-5-ol derivatives (5a-p) prepared by refluxing the ethanolic solution of 1-[1-aryl-5-hydroxy-3-methylpyrazol-4-yl]-butane-1,3-diones (4a-p), hydroxylamine hydrochloride and NaHCO3 and few dro...

The 1,3,4-Oxadiazole ring has emerged as an important class in medicinal chemistry due to its diverse pharmacological properties. This heterocyclic scaffold possesses promising potential for applications in biological activities, material science, agriculture etc. This invention constitutes a substantial advancement...

The present invention discloses the DNA protection ability of newly synthesized thiazoly pyrazoles under UV-irradiations. All compounds (1a-m) effectively protected DNA supercoiled form of DNA as compared to control (C) in which DNA is converted into open circular form from the supercoiled form. ...

The present invention discloses the DNA protection ability of the newly synthesized bis-pyrazoles under UV-irradiations. Among them, 1a-j depicted concentration dependent protection of supercoiled form of DNA as compared to control (C) in which DNA is converted into open circular form supercoiled form. ...

The invention describes the synthesis of 2-(Bromosubstituted arylamino)-4-arylthiazoles via Hantzsch thiazole method by stirring N-Bromosubstituted arylthioureas with various phenacyl bromides in ethanol results in formation of targeted compounds in good yield, where aryl group is C6H5, 4-F-C6H4, 4-Cl-C6H4, 4-Br-C6H...

This invention describes the synthesis of (E)-4-(2-(4-Chloro-3-(trifluoromethyl)phenyl)hydrazono)-5-methyl-2-(4-phenylthiazol-2-yl)-2,4-dihydro-3H-pyrazol-3-one by refluxing the substituted 1-carbothiamide with different phenacyl bromides in ethanol yielded target compounds, where aryl group may be C6H5, p-F-C6H4, p...

The present invention discloses the synthesis and anticancer screening of new compounds, (Z)-N'-(1-(2-hydroxy-6-methyl-4-oxo-4H-pyran-3-yl)ethylidene)-1,3-diphenyl-1H-pyrazole-4-carbohydrazides and their Cu(II) complexes against lung (A549) cancer cell line.

The present invention relates antimalarial screening of the compounds, (Z)-N'-(1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)ethylidene)-1,3-diphenyl-1H-pyrazole-4-carbohydrazides and their Cu(II) complexes against plasmodium falciparum (Pf3D7).

This invention describes the synthesis of 3-(Aryl)-N'-(1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)ethylidene)-1-phenyl-1H-pyrazole-4-carbohydrazides by refluxing 3-(Aryl)-1-phenyl-1H-pyrazole-4-carbohydrazides with dehydroacetic acid (DHA) in ethanol which on treatment with Cu(??) nitrate result in the formation of c...

The present invention discloses anticancer screening of some new edaravone derivatives against lung cancer cell line (A549). The compounds 6a, 6b, 6c & 6g were found to display excellent potential than standard drug, carboplatin against the lung cancer cell line (A549).

ABSTRACT A DEVICE FOR CASHLESS TRANSACTIONS ENABLING ALL KINDS OF CURRENCY USERS AND METHOD THEREOF [043] The present invention relates to the banking industry, specifically to an online money transaction system. The invention combines an electronic device with an advanced mobile application to enable uneducated,...

The present invention outlines the synthesis and characterization of long chain a-acyloxy carboxamides under mild, catalyst-free reaction conditions in one-pot procedure using a multi-component approach. These compounds exhibit antibacterial properties against both gram-negative (E. coli) and gram-positive (S. aureu...

(Z)-4-((11-(2-(4-chlorophenyl)-1H-benzo[d]imidazol-1-yl)undecyl)oxy)-4-oxobut-2-enoic acid as anti-mycobacterial agent. This molecule has been carefully designed to exhibit noteworthy selective antibacterial properties against Mycobacterium smegmatis while minimizing their impact on other microorganisms. ...

The present invention provides a system and method for AI-enabled e-commerce product listing through a five-step wizard interface. A single image upload triggers concurrent AI workflows for image enhancement and product content generation. The process captures all required data through two structured forms, signific...