The present invention relates to efficacy studies of the test compound Etanercept in preventing the arthritic pathology developing in the Tg197 mice. The study claims that the test compound Etanercept, used at 30 mg/kg was significantly effective in preventing the arthritic pathology developing in the Tg197 mice com...

Single nucleotide polymorphs (SNPs) / Copy Number Variations (CNVs) and Epigenome as in the Parsi-Zarathushti genome sequence and corresponding polynucleotides thereof.

The present invention relates to use of novel process of production and recovery of recombinant Monoclonal antibody to HER-2, in biologically active form from fluids, includes but not limited to mammalian host cell culture supernatants by performing fermentation and chromatographic procedure separately and jointly. ...

The present invention relates to novel plants that produce and secrete chitinase and MnSOD as a result of the introduction of DNA sequences encoding chitinase, an enzyme capable of degrading chitin present in fungi and nematodes and MnSOD that confers drought tolerance. Still further it also relates to method of pro...

The present invention relates to a specifically novel recombinant method of production of the omega-3 fatty acid, Eicosapentaenoic acid (EPA) by a potentially safe recombinant organism Saccharomyces cerevisiae. The invention describes the process of bioconversion of oleic acid to EPA through a series of enzymatic co...

The present invention pertains to nutritional or pharmaceutical compositions comprising extracts or concentrates of plants and the mixtures thereof belonging to Lycopersicum sp. with specific reference to Lycopersicum esculentum. The present invention further relates to extracts which are isolated from different par...

The present invention pertains to nutritional or pharmaceutical compositions comprising extracts or concentrates of plants and the mixtures thereof belonging to Citrus sp. with specific reference to Citrus reticulata. The present invention further relates to extracts which are isolated from different parts of Citrus...

The present invention provides a solution to the problem involved in over expression of chemical constituents in plants. It provides a method for attaining transformed plants with higher regeneration efficiency with the potential to over express chemical constituents in plants, preferably steroidal sapogenin, Diosge...

ABSTRACT The present invention relates to a nucleic acid probe or its equivalent probe capable of detecting Variable Number Tandem Repeat (VNTR), a method and use thereof.

ABSTRACT The present invention provides solution to the problems associated with the increased production of proteins. More particularly, the present invention is successful in providing a matrix attachment region sequence[s] or its complementary sequence[s], variant[s] and fragment[s] thereof which can increase th...

ABSTRACT The present invention relates to a System Biology Platform for integrated access to plurality of research like Medicinal Plant research. Stem cell research and research on Microorganisms. More particularly, the invention relates to Adept a System Biology Platform for integrated access to plurality of resea...

ABSTRACT The present invention pertains to nutritional or pharmaceutical compositions comprising extracts or concentrates of plants and the mixtures thereof belonging to Helianthus sp. with specific reference to Phyllanthus emplace. The present invention further relates to extracts which are isolated from different...

ABSTRACT The present invention pertains to nutritional or pharmaceutical compositions comprising extracts or concentrates of plants and the mixtures thereof belonging to Hibiscus sp. with specific reference to Hibiscus sabdariffa. The present invention further relates to extracts which are isolated from different p...

The invention relates to the screening of an unreported strain of Thraustochytrids - A VET producing significant amounts of Docosahexaenoic acid (DHA) and also accumulate their respective intermediate fatty acids in addition to DHA This organism has been isolated from the backwaters of by Pollen Baiting method. Th...

The present invention relates to the use of novel fermentation and chromatographic procedures separately and jointly for the production of recombinant TNK-tPA, a thrombolytic agent in biologically active form from fluids, especially mammalian host cell culture supernatants. The recovery via the novel procedures can ...

ABSTRACT The present invention relates to method for generating plants having altered architecture and to plants so generated and parts of these plants. More particularly, the present invention relates to a method for modifying a plant so as to produce a plant exhibiting an altered phenotype. ...

ABSTRACT The present invention relates to a novel transgenic plant having tolerance to salt stress. The plant is transformed with a recombinant nucleic acid encoding glutei acid decarboxylase isolated from Oryza sativa Still further it also relates to a method of producing the transgenic plants that are salt toler...

The present invention relates to vectors and in particular to compounds of expression for expression of recombinant anti-human TNF alpha monoclonal antibody comprising at least ORF of one of the two polypeptide (heavy and light) chain of the Infliximab, at least one scaffold/matrix attached region (S/MAR), processes...

The present invention relates to the use of novel fermentation and chromatographic procedures separately and jointly for the production and recovery of recombinant Monoclonal antibody to EGFR, in biologically active form from fluids, includes but not limited to mammalian host cell culture supernatants. The recovery ...

The present invention relates to obtain a novel expression vectors and compounds of expression of recombinant anti-human epidermal growth factor receptor monoclonal antibody protein. The present invention further relates to use of novel expression vector carrying Scaffold/Matrix Attachment Region (S/MAR) to produce ...

The present invention relates to a method of enhancing the content of carotenoids and other isoprenoids, preferably of lycopene and or β-carotene, in a plant, plant cell, callus, tissue, fruit, root or other part of a plant and/or a method of increasing the height in a plant, to a plant, plant cell, callus, tissue, ...

The present invention relates to the use of novel fermentation and chromatographic procedures separately and jointly for the production of recombinant soluble Tumour Necrosis Factor Alfa receptor (TNFR) - Human IgG Fc fusion protein, in biologically active form from fluids, especially mammalian host cell culture sup...

The present invention relates to the use of novel fermentation and chromatographic procedures separately and jointly for the production of recombinant Monoclonal antibody to TNF alpha, in biologically active form from fluids, especially mammalian host cell culture supernatants. The recovery via the novel procedures ...

The present invention relates to obtain expression vectors and compounds of expression of recombinant anti-Human Epidermal Growth Factor Receptor-2 (HER-2) monoclonal antibody protein. The present invention further relates to use of novel expression vectors carrying Scaffold/Matrix Attachment Region (S/MAR) for prod...

The present invention relate to vectors and compounds of expression and their construction for high level expression of soluble TNK-tPA (Tenecteplase) protein that can be used as medicaments.

The present invention provides solution to the problems associated with quality control systems for bioactive molecules obtained from plant source. The invention is successful in providing an HPLC method of profiling the active moieties of plant extracts. Additionally, it has developed a visual user interface which ...

The present invention relates to a specifically novel recombinant method of production of the omega-3 fatty acid, Alpha Linolenic acid (ALA) by a potentially safe recombinant organism Saccharomyces cerevisiae. The invention describes the process of bioconversion of oleic acid to ALA through a series of enzymatic con...

The present invention relates to a specifically novel recombinant method of production of the omega-3 fatty acid, Gamma Linolenic acid (GLA) by a potentially safe recombinant organism Saccharomyces cerevisiae. The invention describes the process of bioconversion of oleic acid to GLA through a series of enzymatic con...

The present invention relates to a specifically novel recombinant method of production of the omega-3 fatty acid, Arachidonic acid (ARA) by a potentially safe recombinant organism Saccharomyces cerevisiae. The invention describes the process of bioconversion of oleic acid to ARA through a series of enzymatic convers...

The present invention relates to a specifically novel recombinant method of production of the omega-3 fatty acid, Dihomo Linoleic acid (DGLA) by a potentially safe recombinant organism Saccharomyces cerevisiae. The invention describes the process of bioconversion of oleic acid to DGLA through a series of enzymatic c...

The present invention relates to a method of producing soluble TNFR:Fc by mammalian cell cultures. The method comprises feeding the cells with a primary feed and a secondary feed, wherein the secondary feed includes galactose and mannose. As a result, the sialylation of TNFR-.Fc is increased in comparison to the sia...

The invention describes method of obtaining a plant extract (plant bioactive) capable of showing anti-proliferative activity on cancer cell lines, more particularly on Acute Myeloid Leukemia (AML) cell lines, with minimal effect on normal Peripheral Blood Mononuclear Cells (PBMCs). The bioactive also displays anti-p...

The present invention relates to methods for the cryopreservation of plant cells and to methods for the recovery of plants cells which have been cryopreserved. The invention also relates to plants, viable plant cells and plant cells cultures which have been successfully recovered from cryopreservation. ...

The present invention is an efficient In vitro regeneration of medicinal plant Deschampsia amtarctica by multiple shoots were achieved from basal portion of tillers on modified Murashige and Skoog medium supplemented with 1 mg/1 BAP, Kinetin O.lmg/1, CUS04 0.75 mg/1, 3% Sucrose. Rooting of these plants also achieved...

The present invention relates to a specifically novel recombinant method of production of the omega-3 fatty acid, Docosahexanoic acid (DHA) by a potentially safe recombinant organism Saccharomyces cerevisiae. The invention describes the process of bioconversion of oleic acid to DHA through a series of enzymatic conv...

The present invention relates to a eukaryotic expression vector carrying Scaffold/Matrix Attachment Region(s) (S/MAR). It relates to the use of production of recombinant derbapoietin alpha in increased quantity.

The present invention relates to use of novel bioinformatics approach for predicting and identifying Scaffold/Matrix attachment regions (S/MARs) from different genomic database.

The present invention relates to nutritional or pharmaceutical compositions comprising extracts or concentrates of plants and the mixtures thereof belonging to Arjuna sp. with specific reference to Terminalia arjuna. The present invention further pertains to extracts, which are isolated from different parts of Termi...

This invention deals with the method of extraction, separation and characterization of all the metabolites and the metabolite biomarkers for diagnosis of diseases in biological samples such as, blood plasma sample, urine samples, cell-extracts etc., using metabolomics approach. A less-expensive, robust method of bio...

The present invention describes a differentially expressed protein acting as biomarker for cancer, specifically breast cancer and a method of extracting such protein.

The present invention pertains to nutritional or pharmaceutical compositions comprising extracts or concentrates of plants and the mixtures thereof belonging to Berberis sp. with specific reference to Berberis aristata. The present invention further relates to extracts which are isolated from different parts of Berb...

The present invention relates to a nucleotide sequence having SNP associated with virulence, infectivity and/or latency for all infectious diseases, more particularly tuberculosis. The present invention also includes method for the identification and selection of polymorphisms associated with the virulence and /or i...

The present invention relates to a method of increasing oil content in Euphorbiaceae family members and other latex bearing plant species such as Atrophy species via Agro bacterium-mediated transformation with a glycerol 3-phosphate acyl transferases. Furthermore, the present invention relates to a method of plant m...

The present invention relates of a method of transforming plants of Euphorbiaceae family and other latex bearing species such as Atrophy saps via Agro bacterium. More particularly, the invention disclosed here provides a method of transforming Euphorbiaceae family or other latex bearing plants using leaf explants or...

The present invention relates of a method of increasing oil content in Euphorbiaceae family members and other latex bearing plant species such as Jatropha species via Agrobacterium-mediated transformation with a lysophosphatidic acid acyl transferase. Furthermore, the present invention relates to a method of plant m...

The present invention relates to the use of novel fermentation and chromatographic procedures separately and jointly for the production of a new molecular analogue of recombinant human erythropoietin, which has longer biological half-life compared to r-HuEPO., in biologically active form from fluids, especially mamm...

The present invention relates to the use of novel fermentation and chromatographic procedures separately and jointly for the production of recombinant Monoclonal antibody to VEGF, in biologically active form from fluids, especially mammalian host cell culture supematants.

The present invention relates to the use of novel fermentation and chromatographic procedures separately and jointly for the production of Recombinant Darbepoetin alfa protein, in biologically active form from fluids, especially mammalian host cell culture supernatants.

The present invention further relates to extracts which are isolated from Deschampsia antarctica plant, the preparation of such extracts, the medicaments containing said extracts, and the use of these extracts and constituents for the preparation of a medicament.

ABSTRACT The present invention relates to use of novel bio informatics approach for predicting and identifying Scaffold/Matrix attachment regions (S/MARs) from different genomic database.

ABSTRACT The present invention pertains to nutritional or pharmaceutical compositions comprising extracts or concentrates of plants and the mixtures thereof belonging to Lagerstroemia sp. with specific reference to Lagerstroemia speciosa (Banaba). The present invention further relates to extracts which are isolated...

ABSTRACT The subject invention relates to an improved method of transforming the plant species Brassica juneea. and thereby selecting the transformants with a method of positive selection utilizing Xylose.

The present invention relates to the use of novel fermentation and chromatographic procedures separately and jointly for the production of recombinant Monoclonal antibody to CD20, in biologically active form from fluids, especially mammalian host cell culture supernatants.

The present invention relates to a composition comprising galactomannans having molecular weight of 60000 daltons to 2100000 daltons optionally alongwith acceptable additives.

ABSTRACT; The present invention is aimed at identification, isolation and fractionation of nutritional or pharmaceutical compositions comprising extracts or concentrates of plants and the mixtures thereof belonging to Pinus sp with specific reference to Pinus pineal. The oil and its triglyceride fraction have been ...

Abstract The present invention describes a palatable and orally administrable form of composition comprising proteins, galactomannans and base matrix optionally along with acceptable additives.

The present invention relates to identification and characterization of Phytochemicals and metabolites from Trigonella foenum-graecum extract by Liquid chromatography and Mass spectrometry LC-MS/MS.

The present invention relates to a nucleotide sequence having SNP associated with virulence, infectivity and/or latency for all infectious diseases, more particularly tuberculosis. The present invention also includes method for the identification and selection of polymorphisms associated with the virulence and /or i...

The present invention relates to a nucleotide sequence having SNP associated with virulence, infectivity and/or latency for all infectious diseases, more particularly tuberculosis. The present invention also includes method for the identification and selection of polymorphisms associated with the virulence and /or i...

The present invention relates to a nucleotide sequence having SNP associated with virulence, infectivity and/or latency for all infectious diseases, more particularly tuberculosis. The present invention also includes method for the identification and selection of polymorphisms associated with the virulence and /or i...

ABSTRACT The present invention relates to an extract of Garcinia species optionally along with pharmaceutically acceptable additives and a process for obtaining extract from Garcinia species. Fig: 1-5

The invention describes a highly improved, reproducible and a consistent method of transformation and regeneration that results in obtaining 12-15% transgenic plants. The present invention relates to a method of selecting genetically transformed Sunflower explants based on their ability to utilize Xylose as a sole c...

The present invention relates to vectors and compounds for the expression of recombinant soluble proteins. More particularly, the present invention relates to nucleic acid molecules, expression vectors, and host cells for the expression of recombinant soluble Tumour Necrosis Factor Alfa receptor (TNFR) - Human IgG F...

The present invention relates a nutraceutical or pharmaceutical composition, in combination of 80 unmilled, colored rice varieties. The composition comprises various metabolites, their complete metabolic profiling and study of anti-oxidative capacities of 80 unmilled, colored rice varieties by performing mass spectr...

ABSTRACT The present invention relates to an extract of Punica species optionally along with pharmaceutically acceptable additives; it also relates to a process for obtaining extract from Punica species. Fig: 1-H

The present invention relates to Zinc finger protein (ZNF) 600 expressed in breast cancer patients.

The present invention relates to protein proto-oncogene isoform B expressed in breast cancer patients.

The present invention relate to vectors and compounds of expression for expression of recombinant anti-CD20 monoclonal antibody protein.

The present invention relates to the method of development of stress tolerant plants, which also exhibit self-glucogenic properties and thus can be utilized in the bio ethanol production from the lignocellulosic biomass.

The present invention relate to vectors and compounds of expression for expression of recombinant anti-VEGF monoclonal antibody protein.

ABSTRACT The present invention relates to the isolation of plant nucleic acids and DNA encoding Glutamate decarboxylase, which, emerge in the plants subjected to environmental stress thereby conferring valuable pharma and agro properties, and provides valuable insights for employing CRISPR/Cas genome editing to...

The waves of pastoralist migrations from Airyan'?m Vaejah, the ancient homeland of the present day Zoroastrians-Parsis in the Hyperborean Regions of Northern Siberia and the islands of the circumpolar regions1 led these Indo Europeans to settle in the Eurasian Steppes2 and later, as Indo Iranians in the Fertile Cres...