A Method Of Detecting A Microorganism In A Sample By A Fluorescence Based Detection Method Using Somamers


Updated over 1 year ago

Abstract

The present invention relates to a method of detecting a microorganism in particular Staphylococcus aureus in a sample comprising the steps of a) incubating the sample with a slow off rate modified aptamer (SOMAmer) comprising a fluorescent label b) optionally washing the sample c) analyzing the sample by a fluorescence based detection method. The invention further relates to a slow off rate modified aptamer comprising a fluorescent label wherein the SOMAmer comprises a nucleotide sequence specific for Staphylococcus aureus its use for detecting Staphylococcus aureus cells in a sample and to a microarray or biosensor and a kit comprising at least one of such SOMAmers comprising a fluorescent label.

Information

Application ID 201637031568
Invention Field MICRO BIOLOGY
Date of Application 2016-09-16
Publication Number 09/2017

Applicants

Name Address Country Nationality
MERCK PATENT GMBH Frankfurter Strasse 250 64293 Darmstadt Germany Germany
SOMALOGIC INC. 2945 Wilderness Place Boulder Colorado 80301 U.S.A. U.S.A.

Inventors

Name Address Country Nationality
BAUMSTUMMLER Anne 22 rue des Epices F 67140 Gertwiller France France
MARC KREUCHER Frédéric 61 route du Vin F 67140 Itterswiller France France
LEHMANN David 21 rue des Ardennes F 68280 Andolsheim France France
OCHSNER Urs 1953 Ivy St. Denver CO 80220 U.S.A. U.S.A.
JANJIC Nebojsa 6973 Carter Trail Boulder CO 80301 U.S.A. U.S.A.

Specification

Documents

Name Date
PROOF OF RIGHT [16-09-2016(online)].pdf 2016-09-16
Form 5 [16-09-2016(online)].pdf 2016-09-16
Power of Attorney [16-09-2016(online)].pdf 2016-09-16
Form 3 [16-09-2016(online)].pdf 2016-09-16
Form 20 [16-09-2016(online)].pdf 2016-09-16
Drawing [16-09-2016(online)].pdf 2016-09-16
Other Patent Document [26-11-2016(online)].pdf 2016-11-26
Other Patent Document [03-02-2017(online)].pdf 2017-02-03
Description(Complete) [16-09-2016(online)].pdf 2016-09-16
201637031568-FORM 18 [20-02-2018(online)].pdf 2018-02-20
201637031568-FER.pdf 2020-03-04
201637031568-Information under section 8(2) [06-07-2020(online)]-8.pdf 2020-07-06
201637031568-Information under section 8(2) [06-07-2020(online)].pdf 2020-07-06
201637031568-Information under section 8(2) [06-07-2020(online)]-4.pdf 2020-07-06
201637031568-Information under section 8(2) [06-07-2020(online)]-5.pdf 2020-07-06
201637031568-Information under section 8(2) [06-07-2020(online)]-6.pdf 2020-07-06
201637031568-OTHERS [03-09-2020(online)].pdf 2020-09-03
201637031568-Information under section 8(2) [06-07-2020(online)]-2.pdf 2020-07-06
201637031568-Information under section 8(2) [06-07-2020(online)]-7.pdf 2020-07-06
201637031568-Information under section 8(2) [06-07-2020(online)]-3.pdf 2020-07-06
201637031568-FER_SER_REPLY [03-09-2020(online)].pdf 2020-09-03
201637031568-CLAIMS [03-09-2020(online)].pdf 2020-09-03
201637031568-US(14)-HearingNotice-(HearingDate-25-02-2022).pdf 2022-01-28
201637031568-Information under section 8(2) [06-07-2020(online)]-9.pdf 2020-07-06
201637031568-Information under section 8(2) [06-07-2020(online)]-1.pdf 2020-07-06
201637031568-FORM-26 [15-02-2022(online)].pdf 2022-02-15
201637031568-Correspondence to notify the Controller [15-02-2022(online)].pdf 2022-02-15
201637031568-Sequence listing [04-03-2022(online)].txt 2022-03-04
201637031568-Annexure [04-03-2022(online)].pdf 2022-03-04
201637031568-Written submissions and relevant documents [04-03-2022(online)].pdf 2022-03-04
201637031568-IntimationOfGrant11-03-2022.pdf 2022-03-11
201637031568-PatentCertificate11-03-2022.pdf 2022-03-11

Orders

Applicant Section Controller Decision Date URL