Provided is a biosensor that can perform analysis on the basis of a sample that was non invasively collected from a human body. The biosensor is characterized by comprising: an identification substance (38) that bonds with a detection target substance (40); and an electrode (16) that charges the identification subst...

The present invention is characterized by having a first reception unit (16) and a second reception unit (18) that are for receiving sample liquid and are disposed so as to be separate from each other and in that the first reception unit (16) includes an identification substance (22) that binds to a substance to be ...

An aflatoxin production inhibitor containing a respiratory inhibitor, and a method for controlling aflatoxin contamination using the aflatoxin production inhibitor are provided.

Disclosed is an excellent composition for nucleic acid delivery which is reduced in cytotoxicity and has high nucleic acid introduction efficiency and high gene expression efficiency. Specifically disclosed is a composition for nucleic acid delivery which contains: a block copolymer that has a non charged hydrophili...

Disclosed is a method for producing specific cells by amplifying cells at a desired differentiation stage. The disclosed method is for inducing the differentiation of cells to produce specific cells. In order to amplify cells at a desired differentiation stage, oncogenes are forcibly expressed within cells at the de...

The present invention provides a block copolymer which can act as a carrier that can achieve both the stability of a biotechnology based drug in blood and the release of the biotechnology based drug at an affected area. The block copolymer according to the present invention comprises a polyamino acid chain segment a...

It is revealed that an organ such as pancreas can be regenerated by utilizing a fact that the deficiency of an organ is complemented by injecting an induced pluripotent stem cell (iPS cell) into a developed blastocyst in a blastocyst complementation method. Thus, the present invention has solved the above-described ...

Through a method for producing an optically active sulfoxide of formula 2 or a salt thereof by oxidizing a sulfide of formula 1 or salt thereof by means of hydrogen peroxide using an iron salt in the presence of a chiral ligand of formula 3 a high purity proton pump inhibitor compound having optical activity can be ...

The present invention has an object of providing a method for producing specific cells by amplifying cells in a desired differentiation stage. The present invention provides a method for producing specific cells by inducing differentiation of cells, wherein an oncogene is forcibly expressed in cells in a desired di...

The present invention relates to a protein or peptide printing method, comprising (a) a step for preparing nucleic acids and an acellular protein synthesis system in a microengraved plate composed of microscopic grooves having a specific opening shape, (b) a step for superimposing a substrate on the microengraved...

A tube stack 30 is created by stacking multiple flat tubes 32. Each flat tube 32 is formed to have upper and lower cutout areas 34 and 35 obtained by linearly cutting off an upper arc-shape and a lower arc-shape from a hollow, flat, and circular donut-shape. An emission inflow-side end plate 42 is attached to a casi...

Provided is an electrode for photohydrolysis capable of enlarging a conduction path between a photocatalyst layer and a current collection layer without inhibiting absorption of light by a photocatalyst. This electrode for photohydrolysis is provided with a photocatalyst layer (10) a current collection layer (30) an...

Provided is an endoparasite control agent that includes as an active ingredient a carboxamide derivative represented by general formula (I) or salts thereof in order to provide a novel endoparasite control agent such as an insecticide or antiprotozoal agent having significant control efficacy against endoparasites o...

Provided is an endoparasite control agent that includes as an active ingredient a heterocyclic carboxamide derivative represented by general formula (I) or salts thereof in order to provide a novel endoparasite control agent such as an insecticide or antiprotozoal agent having significant control efficacy against en...

[Problem] To provide a gel which can be produced in a short time, has controlled properties such as modulus and expansion pressure, and has a low polymer concentration. [Solution] A process for producing a polymer gel in which gel-precursor clusters have been crosslinked with one another to form a three-dimensional ...

The object of the invention is to provide an immunological reconstitution promoter or a prophylactic agent for infections for use in allogeneic hematopoietic stem cell transplantation therapy for tumors. The promoter or prophylactic agent enables the amelioration of delayed immune reconstitution or the preventi...

The present invention relates to an antibody binding to Claudin6 (CLDN6) expressed on a cell membrane. The antibody of the present invention recognizes human CLDN6 present in a native form on cell membrane surface and exhibits cytotoxicity through ADCC and/or CDC activities against cancer cell lines highly expressin...

An object of the present invention is to provide a method of promoting polynucleation of megakaryocytic cells to form polynucleated megakaryocytic cells with higher polynucleation and to provide a method for efficiently producing platelets from polynucleated megakaryocytic cells. The present invention is a method fo...

Disclosed is an isoquinuclidine derivative which enables to easily synthesize oseltamivir or an analogue thereof. Specifically disclosed is an isoquinuclidine derivative represented by the formula (1) below or a mirror image structure of the formula (1). (1) (In the formula (1), A represents a protective group of a ...

An object of the present invention is to provide a polyrotaxane-containing solution by finding a good for polyrotaxanes, and more particularly, to provide a polyrotaxane-containing solution by finding a good solvent for polyrotaxanes with a cyclodextrin as the cyclic molecule (s) . The present invention provides a ...

A process for producing a polyrotaxane in a high yield and at a satisfactory cost without using a large excess of a pseudopolyrotaxane and/or without using a large excess of an activated reagent. The process for polyrotaxane production comprises: a clathration step in which a carboxylated polyethylene glycol which i...

Abstract An electro-tactile display includes an electrode substrate provided with a plurality of stimulation electrodes, a conductive gel layer positioned between the stimulation electrodes and the skin of a wearer, a switching circuit section electrically connected to the stimulation electrodes, a stimulation patt...

Disclosed are a novel polyrotaxane having a main chain backbone essentially composed of -Si-O-, and a method for producing such a novel polyrotaxane. Also disclosed are a polyrotaxane having stretchability and/or viscoelasticity, while exhibiting oxygen permeability, heat resistance, chemical resistance, environment...

Disclosed is a novel amide compound or a salt thereof which has a biofilm formation inhibitory activity or an activity of separating and removing an already-made biofilm. Also disclosed is a biofilm formation inhibitor or biofilm remover containing such an amide compound or a salt thereof as an active ingredient. Th...

It is intended to provide a net-like structure enclosing hematopoietic progenitor cells, a method for preparing the net-like structure, and a method for efficiently preparing blood cells such as mature megakaryocytes and platelets from the net-like structure. The invention provides a net-like structure enclosing hem...

The cellulose nanofiber production method of the present invention comprises an oxidation treatment step for oxidizing native cellulose in a neutral or acidic reaction solution containing an N-oxyl compound and an oxidizing agent that oxidizes aldehyde groups, and a dispersion step for dispersing the native cellulos...

Disclosed is a novel asymmetric ligand which can be synthesized by a short process at low cost and is capable of exhibiting higher catalytic activity and enantioselectivity than the conventional ligands derived from sugars. Also disclosed are a method for producing such an asymmetric ligand, and a catalyst using suc...

A protein, wherein the protein is derived from a basidiomycete, has an endoglucanase activity, and has a molecular weight of 18 kDa which is measured by 5 SDS-PAGE.

ABSTRACT "METHOD FOR IDENTIFYING GENE WITH VARYING EXPRESSION LEVELS" This invention relates to a method for searching for a genetic polymorphism for identifying a gene whose expression level is different between alleles and to a method for searching for a phenotype-associated genetic polymorphism. More particularl...

To provide a positive electrode active material containing a pyrophosphate compound, ensuring that mixing of impurities is easily prevented to facilitate the synthesis and a high capacity battery is obtained, and a lithium ion battery using the positive electrode material. That is, the present invention relates to ...

2m1152522342345Provided is a composition for maintaining platelet function that has as the active ingredient a compound represented by general formula (I) [in the formula: X indicates a phenylene group; Y indicates a hydrogen atom or (CH)R; m indicates any integer from 0 to 4; R indicates NRCOR  NRSOR or NRR; R indi...

To provide a method for producing a sugar, a method for producing ethanol, and a method for producing lactic acid, in all of which enzymatic saccharification can be efficiently performed to thereby respectively improve the production efficiency of sugar, the production efficiency of ethanol, and the production ef...

The present application proposes an oral cavity sensor with which it is possible to carry out an analysis of tongue operations in greater detail than before. With an oral cavity sensor (1) comprising even a sensor element (7) having a mechanical configuration with which each external force component in three axes is...

Provided is a high-quality aptamer against IL-17. An aptamer possessing an inhibitory activity against IL-17; a complex comprising an aptamer possessing a binding activity or inhibitory activity against IL-17 and a functional substance (for example, affinity substances, substances for labeling, enzymes, drug delive...

The purpose of the present invention is to provide an efficient and versatile method for imparting an additional binding activity to an antibody through inserting a peptide sequence into the antibody. The present invention provides a method for imparting an antibody with a binding capacity for a second target molecu...

The present invention provides: an agent for the treatment or prevention of HTLV-1-associated myelopathy (HAM), the agent containing an RGMa inhibitor; and a HAM treatment method including the administration of a pharmacologically effective amount of an RGMa inhibitor to an HTLV-1-associated myelopathy (HAM) patient...

[Problem] The present invention addresses the problem of providing a gel material comprising a solvophilic polymer having a micrometer-scale porous structure. [Solution] A polymer gel in which solvophilic polymer units are cross-linked to each other, wherein the polymer gel contains a solvent, and has a three-dimens...

With dedicated research, the present inventors discovered that not only the LGR7 gene but also the LGR7 protein are highly expressed in clear cell adenocarcinoma cells of ovarian cancer.  Furthermore, the present inventors found that anti-LGR7 antibodies have antibody-dependent cell-mediated cytotoxicity (ADCC) acti...

Disclosed are transplantation cells for an immunotherapy, which are applicable to a wider variety of patients compared to conventional transplantation cells for immunotherapies, and which can survive transiently so that severe GVH disease cannot be induced. Specifically disclosed is a pharmaceutical composition cont...

The present invention provides a vesicle for delivering a drug to the brain a conjugate a composition containing same and a method for administering same. A composition for administration to a subject according to a dosing regimen the composition containing a carrier for drug delivery wherein the dosing regime...

The purpose of the present invention is to provide a novel medicinal use in regeneration medicine said medicinal use comprising using pluripotent stem cells (Muse cells). Provided is a cell preparation for treating skin ulcer said cell preparation comprising SSEA 3 positive pluripotent stem cells isolated from a mes...

Provided are: a lactic acid bacteria containing composition having on the cell surfaces thereof a polypeptide derived from the E7 protein of human papilloma virus (HPV) wherein the amount of polypeptide derived from the E7 protein of HPV contained in the lactic acid bacteria containing composition is 0.03 µg 1.0 µg ...

A greenhouse framework 22 is assembled out of framework materials 24 such as typical pipe and the outer periphery of the greenhouse framework 22 is covered with a sheet outer surface member 30 formed from a vinyl sheet; a sheet inner surface member 32 is formed on the inside of the greenhouse framework 22 by a heat ...

This production method is for producing a composite member which is formed by joining a base material and a resin member to each other. The production method comprises: a surface treatment step for forming micro-order or nano-order reliefs on a surface of a base material; and a joining step for joining by injection ...

The present invention sequentially and repeatedly receives a plurality of types of information that can change with the time of day including position information obtained using a satellite signal and correlates and records the received plurality of types of information with time-of-day information. ...

The present invention provides a small and light knee joint that has good energy efficiency and is able to move in a wider movement range. The present invention also provides a comparatively cheap, active knee joint. A drive unit 1 moves a driven member 21. An elastic member 22 is disposed between the driven member ...

Provided is a method for presenting a cyclic peptide, which has a chemically crosslinked structure for forming an intramolecular cyclic structure, on a protein having a loop structure, said method comprising substituting the chemically crosslinked structure of the cyclic peptide by two amino acid residues constituti...

Provided is a cell preserving vessel in which cells are unlikely to be damaged when being preserved. This cell preserving vessel 1 comprises: a vessel body 10 that is constituted by a flexible resin member and has a cell accommodating part 11; a cell introducing tube 20 which is connected to the vessel body 10 and t...

A biosensor that can perform analysis based on a sample noninvasively collected from a human body is provided. The biosensor comprises an identification substance (38) that binds to a substance to be detected (40), and an electrode (16) charged with a charge of the identification substance (38), comprises an inhibi...

[Problem] To provide a fluorescent probe capable of detecting breast cancer, lung cancer, and squamous cell cancer. [Solution] A fluorescent probe for detecting breast cancer and benign tumors of the breast, the probe containing a compound represented by general formula (I) or a salt thereof.

The present invention provides a small and light knee joint that has good energy efficiency and is able to move in a wider movement range. The present invention also provides a comparatively cheap, active knee joint. A drive unit 1 moves a driven member 21. An elastic member 22 is disposed between the driven member ...

The present invention discloses a composition of a serum-free medium and a culturing method suited for culturing human cells. The present invention provides a method for culturing human cells. The method comprises bringing human cells into contact with a polyalkylene glycol modified by a copolymer of a polyvinyl cap...

Establishment of pancreatic islet-like insulin producing cells by inducing differentiation of ES/iPS cells has been reported. However, no technique has been developed so far for producing functional pancreatic islet insulin-positive cells in a large amount. In addition, there are concerns regarding rejection respons...

[Problem] The problem addressed is to provide novel uses to which a high-molecular-weight gel material with a porous structure on the nanometer scale can advantageously be applied. [Solution] A gel material for regenerative medicine includes a high-molecular-weight gel formed by mutually cross-linking hydrophilic po...

According to the present invention, a polymeric complex includes a protein and a block copolymer represented by formula (1).

The wireless power receiving system (1) is provided with: a power receiving device (5) having a power receiving coil (51) that receives electric power wirelessly supplied from a power transmitting coil (41) of a power transmitting device (4) installed on a road surface, at least a part of the power receiving coil (5...

This wireless power receiving system 1 is provided with a power receiving device 5, comprising a power receiving coil 51 that receives electrical power supplied wirelessly from a power transmission coil 41 of a power transmission device 4 disposed in a road surface, at least part of the power receiving coil 51 being...

A wireless power receiving system 1 comprising: a power receiving device 5 that has a power receiving coil 51 that receives power transmitted wirelessly from a power transmission coil 41 in a power transmission device 4 arranged on a road surface, at least part of the power receiving coil 51 being housed in a wheel ...

The wireless power receiving system 1 is provided with: a power receiving device 5 having a power receiving coil 51 that receives electric power wirelessly supplied from a power transmitting coil 41 of a power transmitting device 4 installed on a road surface, wherein at least a part of the power receiving coil 51 i...

A wireless power supply system 1 includes a power transmission device 2 and a power reception device 3. The power transmission device 2 is installed in a road 4, and comprises a power transmission coil 21 that wirelessly transmits electric power, said power transmission device 2 being configured so that, upon being ...

The purpose of the present invention is to provide a novel RNA molecule, a novel chimeric NA molecule, a novel double-stranded RNA molecule, and a novel double-stranded chimeric NA molecule. That is, one embodiment of the present invention is an RNA molecule used in an RNA interference method using, as a target gene...

[Problem] To provide a safe and effective hemostatic method, blood vessel occlusion method, tissue covering method, or body fluid coagulation method, using a polymer material which is a non-biologically derived synthetic product. [Solution] A solution (pre-gel solution) is prepared, having specific pH condition and ...

Provided are a nucleic acid with improved ability to inhibit the expression of the MEX3B gene with low occurrence of cytotoxicity side effects, an MEX3B gene expression inhibiting agent that includes the nucleic acid, a method for inhibiting MEX3B gene expression, and a prophylactic or therapeutic drug for a disease...

Provided is an electrolyte solution wherein a metal salt and a solvent are present in novel states. An electrolyte solution according to the present invention contains a salt wherein an alkali metal an alkaline earth metal or aluminum serves as cations and an organic solvent having a hetero element. This electro...

An adiponectin secretion regulator capable of efficiently expressing the effects of adiponectin while avoiding the deleterious increase of appetite concomitant with adiponectin is provided along with food and drink products functional food products cosmetics pharmaceuticals and animal feed having such adiponectin se...

[Problem] To provide a novel compound having great potential as a prodrug-type anticancer agent. [Solution] A compound represented by general formula (I) or a salt thereof

The present invention relates to a process for the preparation of a zeolitic material having a CHA-type framework structure comprising YO2 and X2O3, wherein said process comprises: (1) providing a mixture comprising one or more sources for YO2, one or more sources for X2O3, one or more tetraalkylammonium cation R1R2...

The present invention provides D39-derived mutant PspA that does not undergo deamination and maintains molecular stability even at near-neutral pH. Specifically, the present invention is the following protein (a) or (b). (a) A protein that includes the amino acid sequence represented by sequence no. 2 and that has p...

This information processing system is configured so as to execute a reading step and a determination step. In the reading step, a first electrocardiogram waveform that has been input and includes an electrocardiogram waveform of a user is read. In the determination step, a heart failure stage of the user is determin...

A position i n formation processing apparatus (10) comprising : a receiving device (32) that receives a signal including a satellite signal ; an accepting device (13) that repeatedly acquires sequential information including a plurality of recording target information changeable with time, including position informa...

The present disclosure provides a method that is for detecting a biomolecule, the method comprising: providing an electrode 101, and an aptamer 102 that is disposed in the vicinity of the electrode 101, that specifically binds to the target biomolecule, and that has an electric charge; introducing a cation mediator ...

The present invention pertains to an antibody binding to an intestinal bacterium, an antigen-binding fragment thereof and use of the same. Further, the present invention discloses a nucleic acid encoding the antibody or an antigen-binding fragment thereof, an expression vector containing the nucleic acid, a cell con...

The purpose of the present invention is to provide a novel RNA molecule. An RNA molecule for RNA interference for which the target gene is a mutant allele that has a point mutation. The RNA molecule (1) has a base sequence that is complementary to a coding region of the mutant allele, and (2) counting from the base ...

The purpose of the present invention is to provide a novel RNA molecule. An RNA molecule, which is for an RNA interference method using a mutant allele having a point mutation as a target gene, wherein: (1) a base sequence complementary to a coding region of the mutant allele is included; and (2) counting from the m...

The present disclosure provides a novel method for manufacturing a thin film, with which it is possible to control the density of a thin film obtained. The method of the present disclosure relates to a method for manufacturing a thin film, comprising the following steps (a) to (e) in this order: (a) providing an ele...

A method for producing beta zeolite, said method comprising contacting a beta zeolite matrix powder, which is synthesized without using an organic structure-directing agent, with an aqueous alkaline solution with a pH value of 12 or higher. It is preferred to set the liquid temperature of the aqueous alkaline soluti...

[Problem] The present invention addresses the problem of providing a novel artificial slime-like polymer material which has stability with respect to an external solvent without changing the chemical compositions of the main chain skeleton, a solvent and the like that constitute the polymer material, and without det...

Provided is an antibody that exhibits pH dependence and specifically binds to a sulfated glycosaminoglycan (sGAG). An antibody specifically binding to a sulfated glycosaminoglycan that is at least one selected from the group consisting of the following (1) to (3): (1) an antibody that contains a heavy chain having C...

[Problem] To provide a dispensing device capable of improving the dispensing accuracy of a liquid-phase sample. [Solution] A dispensing device 1 according to an embodiment comprises: a cylindrical first flow passage 11 which has a cylindrical main body part 14, an opening 15 formed in the main body part 14, and a li...

[Problem] The present invention addresses the problem of providing a technique of inhibiting ingress of scar tissue in treatment of a tendon or ligament, thereby promoting healing of cells in the tendon to efficiently restore the original function of the tendon. [Solution] A gel material that is for inhibiting expre...

Provided is a health assisting device comprising: an acquiring unit for acquiring first data comprising health-related data relating to a subject user, the first data not changing or changing, in a predetermined period, by an amount less than a predetermined amount, and second data comprising health-related data rel...

Provided are: cellulose porous particles which have large surface areas on which cells can be attached, and on which cells can be adhered easily, and which rarely undergo the detachment of cells when the cells are cultured at a high density; and a microcarrier for culture use, which comprises the cellulose porous pa...

[Problem] The present invention addresses the problem of providing a novel artificial slime-like polymer material, the fluidity characteristics of which can be controlled without changing the chemical compositions of the main chain skeleton, a solvent and the like that constitute the polymer material. [Solution] It ...

The present invention provides an IL13RA2-targeting herpes simplex virus in which an anti-IL13RA2 antibody or an antigen-binding fragment thereof is presented on the viral surface. Also provided is an anti-IL13RA2 antibody or an antigen-binding fragment thereof capable of specifically recognizing tumor cells. ...

[Problem] To provide a novel gel that excels in physical characteristics such as toughness and elastic modulus and that has a fibrous shape, as well as a fibrous polymer material for obtaining said gel. [Solution] Provided is a fibrous polymer material having an anisotropic swelling property in water, said fibrous p...

A composite comprising an oxyanion and an organic cation obtained through ionization of a compound having at least two amino groups or guanidino groups, wherein the organic cation and the oxyanion are bound by an ionic bond and a hydrogen bond.

The present disclosure provides an immunoglobulin multimer, a method for producing the same, and a modified immunoglobulin capable of forming an immunoglobulin multimer. In another aspect, the present disclosure has an effect of providing: a method for utilizing an immunoglobulin multimer or a modified immunoglobuli...